Suchergebnisse - "Cabrales, Pedro"

PubPharm (50)

1

TGF-β : the apex predator of immune checkpoints

enthalten in: Future oncology (London, England) | 2023

von Oronsky, B. | Cabrales, P. | Alizadeh, B. | +4

2

A Review of RRx-001 : A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation

enthalten in: Drugs | 2023

von Jayabalan, N. | Oronsky, B. | Cabrales, P. | +6

3

RRx-001 : a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist

enthalten in: Frontiers in oncology | 2023

von Oronsky, B. | Takahashi, L. | Gordon, R. | +3

4

Phase 1 pilot study of RRx-001 + nivolumab in patients with advanced metastatic cancer (PRIMETIME)

enthalten in: Frontiers in immunology | 2023

von Reid, T. | Oronsky, B. | Caroen, S. | +4

5

The small molecule NLRP3 inhibitor RRx-001 potentiates regorafenib activity and attenuates regorafenib-induced toxicity in mice bearing human colorectal cancer xenografts

enthalten in: American journal of cancer research | 2022

von Reid, T. | Oronsky, B. | Abrouk, N. | +2

6

Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas

enthalten in: Journal of drug targeting | 2021

von Oronsky, B. | Reid, T. | Cabrales, P.

7

Discovery of RRx-001, a Myc and CD47 Downregulating Small Molecule with Tumor Targeted Cytotoxicity and Healthy Tissue Cytoprotective Properties in Clinical Development

enthalten in: Journal of medicinal chemistry | 2021

von Oronsky, B. | Guo, X. | Wang, X. | +9

8

RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature

enthalten in: International journal of molecular sciences | 2021

von Jani, V. | Asaro, R. | Oronsky, B. | +1

9

RRx-001, a downregulator of the CD47- SIRPα checkpoint pathway, does not cause anemia or thrombocytopenia

enthalten in: Expert opinion on drug metabolism & toxicology | 2021

von Oronsky, B. | Cabrales, P. | Caroen, S. | +4

10

In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical benefit

enthalten in: Translational lung cancer research | 2021

von Tomita, Y. | Oronsky, B. | Abrouk, N. | +7

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