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PubPharm (23)
1
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization
enthalten in:
Science translational medicine
| 2024
von
Chen, J.
|
Laverty, D.
|
Talele, S.
| +16
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2
Differential distribution of the DNA-PKcs inhibitor peposertib selectively radiosensitizes patient-derived melanoma brain metastasis xenografts
enthalten in:
Molecular cancer therapeutics
| 2024
von
Ji, J.
|
Dragojevic, S.
|
Callaghan, C.
| +17
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3
Delivery versus Potency in Treating Brain Tumors : BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma
enthalten in:
Molecular cancer therapeutics
| 2024
von
Zhang, W.
|
Vaubel, R.
|
Oh, J.
| +7
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4
WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models
enthalten in:
Neuro-oncology advances
| 2023
von
Conage-Pough, J.
|
Stopka, S.
|
Oh, J.
| +17
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5
Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390 : Implications for the Treatment of Brain Tumors
enthalten in:
The Journal of pharmacology and experimental therapeutics
| 2022
von
Talele, S.
|
Zhang, W.
|
Chen, J.
| +4
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6
Single-cell based elucidation of molecularly-distinct glioblastoma states and drug sensitivity
enthalten in:
bioRxiv.org
| 2022
von
Ding, H.
|
Burgenske, D.
|
Zhao, W.
| +18
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7
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma
enthalten in:
Neuro-oncology
| 2022
von
Mladek, A.
|
Yan, H.
|
Tian, S.
| +13
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8
Central Nervous System Delivery of the Catalytic Subunit of DNA-Dependent Protein Kinase Inhibitor Peposertib as Radiosensitizer for Brain Metastases
enthalten in:
The Journal of pharmacology and experimental therapeutics
| 2022
von
Talele, S.
|
Zhang, W.
|
Oh, J.
| +5
ErratumIn: J Pharmacol Exp Ther. 2022 Dec;383(3):251. - PMID 36396351
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9
Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy
enthalten in:
Science advances
| 2022
von
Ng, T.
|
Hu, H.
|
Kronister, S.
| +23
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10
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules
enthalten in:
Neuro-oncology
| 2022
von
Burgenske, D.
|
Talele, S.
|
Pokorny, J.
| +19
CommentIn: Neuro Oncol. 2021 Nov 27;:. - PMID 34850193
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Thema
20
Journal Article
10
Research Support, N.I.H., Extramural
7
Research Support, Non-U.S. Gov't
7
glioblastoma
4
EC 2.7.11.1
4
Temozolomide
4
YF1K15M17Y
3
Ataxia Telangiectasia Mutated Proteins
2
Antineoplastic Agents, Alkylating
2
Depatux-M
2
EGFR
2
Isoxazoles
2
L423PRV3V3
2
Pharmaceutical Preparations
2
Pyrazines
2
Tumor Suppressor Protein p53
2
berzosertib
2
blood-brain barrier
1
1HG84L3525
1
570
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Erscheinungszeitraum
18
2020-
5
2010-2019
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23
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