Suchergebnisse - "Broome, Martin"

PubPharm (3)

1

In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models

enthalten in: Molecular cancer therapeutics | 2016

von Hughes, P. | Rex, K. | Caenepeel, S. | +17

2

Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity

enthalten in: Journal of medicinal chemistry | 2016

von Boezio, A. | Copeland, K. | Rex, K. | +20

3

Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors

enthalten in: Bioorganic & medicinal chemistry letters | 2012

von Bode, C. | Boezio, A. | Albrecht, B. | +11

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