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PubPharm (17)
1
From recipe to research : introducing undergraduate students to the nature of science using a hybrid practical course centred on drug discovery for neglected diseases
enthalten in:
Drug discovery today
| 2021
von
Wijtmans, M.
|
Edink, E.
|
van Linden, O.
| +4
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2
Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)
enthalten in:
Bioorganic & medicinal chemistry
| 2019
von
de Heuvel, E.
|
Singh, A.
|
Boronat, P.
| +14
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3
Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity
enthalten in:
International journal for parasitology. Drugs and drug resistance
| 2019
von
Botros, S.
|
William, S.
|
Sabra, A.
| +17
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4
Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity
enthalten in:
Journal of medicinal chemistry
| 2018
von
Blaazer, A.
|
Singh, A.
|
de Heuvel, E.
| +24
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5
Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases
enthalten in:
Analytical biochemistry
| 2016
von
Siderius, M.
|
Shanmugham, A.
|
England, P.
| +5
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6
Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases
enthalten in:
Analytical biochemistry
| 2016
von
Siderius, M.
|
Shanmugham, A.
|
England, P.
| +5
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7
Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane
enthalten in:
European journal of medicinal chemistry
| 2015
von
Bach, T.
|
Jensen, A.
|
Petersen, J.
| +7
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8
Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits
enthalten in:
Journal of biomolecular screening
| 2015
von
Blaazer, A.
|
Orrling, K.
|
Shanmugham, A.
| +9
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9
Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits
enthalten in:
Journal of biomolecular screening
| 2015
von
Blaazer, A.
|
Orrling, K.
|
Shanmugham, A.
| +9
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10
Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane
enthalten in:
European journal of medicinal chemistry
| 2015
von
Bach, T.
|
Jensen, A.
|
Petersen, J.
| +7
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European journal of medicinal chemistry
2
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Drug discovery today
1
International journal for parasitology. Drugs a...
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Nature <London>
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Thema
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Journal Article
7
Research Support, Non-U.S. Gov't
5
3',5'-Cyclic-AMP Phosphodiesterases
5
EC 3.1.4.17
4
PDEB1 protein, Trypanosoma brucei
4
Protozoan Proteins
3
Phosphodiesterase Inhibitors
2
Cyclic Nucleotide Phosphodiesterases, Type 4
2
Ligands
2
PDE4D protein, human
2
Phosphodiesterase
2
Review
2
Small Molecule Libraries
2
antiparasitic activity
2
cell-based screening
2
fragment-based drug discovery (FBDD)
2
neglected tropical diseases (NTDs)
2
phenotypic drug discovery (PDD)
2
phenotypic screening
2
phosphodiesterase (PDE) inhibitors
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2020-
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2010-2019
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2000-2009
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