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PubPharm (22)
1
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML
enthalten in:
Blood
| 2024
von
Bourgeois, W.
|
Cutler, J.
|
Aubrey, B.
| +22
CommentIn: Blood. 2024 Apr 11;143(15):1438-1439. - PMID 38602697
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2
Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses
enthalten in:
Cell death and differentiation
| 2024
von
La Marca, J.
|
Aubrey, B.
|
Yang, B.
| +16
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3
SOHO State of the Art and Next Questions : Treatment of Higher-Risk Myelodysplastic Syndromes
enthalten in:
Clinical lymphoma, myeloma & leukemia
| 2022
von
Aubrey, B.
|
Brunner, A.
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4
Evidence-Based Minireview : Clinical utilization of panel-based molecular testing for patients with AML
enthalten in:
Hematology. American Society of Hematology. Education Program
| 2022
von
Aubrey, B.
|
Brunner, A.
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5
MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
enthalten in:
Cancer discovery
| 2022
von
Hemming, M.
|
Benson, M.
|
Loycano, M.
| +9
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6
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1
enthalten in:
Cell death and differentiation
| 2022
von
Aubrey, B.
|
Brennan, M.
|
Diepstraten, S.
| +5
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7
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia
enthalten in:
Nature cancer
| 2022
von
Aubrey, B.
|
Cutler, J.
|
Bourgeois, W.
| +22
CommentIn: Nat Cancer. 2022 May;3(5):528-529. - PMID 35624338
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8
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
enthalten in:
Blood
| 2021
von
Thijssen, R.
|
Diepstraten, S.
|
Moujalled, D.
| +33
CommentIn: Blood. 2021 May 20;137(20):2711-2712. - PMID 34014291
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9
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia
enthalten in:
Blood
| 2019
von
McRae, H.
|
Garnham, A.
|
Hu, Y.
| +24
CommentIn: Blood. 2019 Apr 18;133(16):1698-1700. - PMID 31000514
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10
Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development
enthalten in:
Genes & development
| 2018
von
Aubrey, B.
|
Janic, A.
|
Chen, Y.
| +12
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Thema
19
Journal Article
16
Research Support, Non-U.S. Gov't
10
Tumor Suppressor Protein p53
6
Myeloid Cell Leukemia Sequence 1 Protein
5
Apoptosis Regulatory Proteins
4
Antineoplastic Agents
4
Bcl-2-Like Protein 11
4
Proto-Oncogene Proteins c-bcl-2
4
Transcription Factors
4
Tumor Suppressor Proteins
3
PUMA protein, mouse
3
Review
2
Bcl2l11 protein, mouse
2
Chromatin
2
EC 2.3.1.48
2
Histone Acetyltransferases
2
Homeodomain Proteins
2
Isoquinolines
2
MCL-1
2
MCL1 protein, human
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Erscheinungszeitraum
8
2020-
14
2010-2019
Erscheinungsjahr(e)
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Sprache
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Englisch
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