Suchergebnisse - "Asgharnejad, Mahnaz"

PubPharm (34)

1

Population pharmacokinetics, enzyme occupancy, and pharmacodynamic modeling of soticlestat in patients with developmental and epileptic encephalopathies

enthalten in: Clinical and translational science | 2024

von Yin, W. | Facius, A. | Asgharnejad, M. | +2

2

Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers

enthalten in: British journal of clinical pharmacology | 2024

von Yin, W. | Ballard, T. | Zhu, S. | +9

3

Randomized controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in adults with complex regional pain syndrome

enthalten in: Pain medicine (Malden, Mass.) | 2023

von Ratcliffe, S. | Arkilo, D. | Asgharnejad, M. | +2

4

Population pharmacokinetics, enzyme occupancy, and 24S-hydroxycholesterol modeling of soticlestat, a novel cholesterol 24-hydroxylase inhibitor, in healthy adults

enthalten in: Clinical and translational science | 2023

von Yin, W. | Facius, A. | Wagner, T. | +4

5

The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial

enthalten in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 2023

von O'Donnell, P. | Dong, C. | Murthy, V. | +12

6

Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE)

enthalten in: Epilepsy & behavior : E&B | 2023

von Demarest, S. | Jeste, S. | Agarwal, N. | +4

7

A phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox-Gastaut syndrome (ELEKTRA)

enthalten in: Epilepsia | 2022

von Hahn, C. | Jiang, Y. | Villanueva, V. | +5

8

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers

enthalten in: Translational psychiatry | 2022

von Dijkstra, F. | O'Donnell, P. | Klaassen, E. | +6

9

A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies

enthalten in: Epilepsy research | 2021

von Halford, J. | Sperling, M. | Arkilo, D. | +5

10

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

enthalten in: Translational psychiatry | 2021

von O'Donnell, P. | Dijkstra, F. | Damar, U. | +15