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PubPharm (140)
1
Characterizing the Nonlinear Pharmacokinetics and Pharmacodynamics of BI 187004, an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, in Humans by a Target-Mediated Drug Disposition Model
enthalten in:
Journal of clinical pharmacology
| 2024
von
Yuan, X.
|
An, G.
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2
Pharmacokinetics and Pharmacodynamics of GalNAc-Conjugated siRNAs
enthalten in:
Journal of clinical pharmacology
| 2024
von
An, G.
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3
A Quantitative Systems Pharmacology Model of the Incretin Hormones GIP and GLP1, Glucagon, Glucose, Insulin, and the Small Molecule DPP-4 Inhibitor, Linagliptin
enthalten in:
Journal of pharmaceutical sciences
| 2024
von
Wu, N.
|
An, G.
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4
Pharmacokinetics and Pharmacodynamics of GalNAc‐Conjugated siRNAs
enthalten in:
The Journal of Clinical Pharmacology
| 2024
von
An, G.
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5
Population Target-Mediated Pharmacokinetic/Pharmacodynamic Modeling to Evaluate SPI-62 Exposure and Hepatic 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD-1) Inhibition in Healthy Adults
enthalten in:
Clinical pharmacokinetics
| 2023
von
Wu, N.
|
Katz, D.
|
An, G.
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6
Population Target-Mediated Pharmacokinetic/Pharmacodynamic Modeling to Evaluate SPI-62 Exposure and Hepatic 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD-1) Inhibition in Healthy Adults
enthalten in:
Clinical pharmacokinetics
| 2023
von
Wu, N.
|
Katz, D.
|
An, G.
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7
Population Target-Mediated Pharmacokinetic/Pharmacodynamic Modeling to Evaluate SPI-62 Exposure and Hepatic 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD-1) Inhibition in Healthy Adults
enthalten in:
Clinical pharmacokinetics
| 2023
von
Wu, N.
|
Katz, D.
|
An, G.
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8
Population Target-Mediated Pharmacokinetic/Pharmacodynamic Modeling to Evaluate SPI-62 Exposure and Hepatic 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD-1) Inhibition in Healthy Adults
enthalten in:
Clinical pharmacokinetics
| 2023
von
Wu, N.
|
Katz, D.
|
An, G.
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9
Population pharmacokinetics and target attainment analyses to identify a rational empirical dosing strategy for cefepime in critically ill patients
enthalten in:
The Journal of antimicrobial chemotherapy
| 2023
von
An, G.
|
Creech, C.
|
Wu, N.
| +12
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10
Importance of Target-Mediated Drug Disposition (TMDD) of Small-Molecule Compounds and Its Impact on Drug Development-Example of the Class Effect of HSD-1 Inhibitors
enthalten in:
Journal of clinical pharmacology
| 2023
von
An, G.
|
Katz, D.
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11
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Anti-Bacterial Agents
9
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9
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9
pharmacokinetics
9
population pharmacokinetics
7
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7
Protein Kinase Inhibitors
6
11-beta-Hydroxysteroid Dehydrogenase Type 1
6
ATP Binding Cassette Transporter, Subfamily G, ...
6
ATP-Binding Cassette Transporters
6
Benzimidazoles
6
EC 1.1.1.146
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OMP2H17F9E
6
Randomized Controlled Trial
6
clinical pharmacokinetics
6
oxfendazole
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Erscheinungszeitraum
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2020-
84
2010-2019
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