Suchergebnisse - "Al-Sha'er, Mahmoud A"

PubPharm (11)

1

Discovery of new PKN2 inhibitory chemotypes via QSAR-guided selection of docking-based pharmacophores

enthalten in: Molecular diversity | 2023

von Al-Sha'er, M. | Basheer, H. | Taha, M.

2

Pharmacophore Modeling of Targets Infested with Activity Cliffs via Molecular Dynamics Simulation Coupled with QSAR and Comparison with other Pharmacophore Generation Methods : KDR as Case Study

enthalten in: Molecular informatics | 2022

von Abudayah, A. | Daoud, S. | Al-Sha'er, M. | +1

3

Elaboration of Novel TTK1 Inhibitory Leads via QSAR-Guided Selection of Crystallographic Pharmacophores Followed By In Vitro Assay

enthalten in: Current computer-aided drug design | 2021

von Al-Sha'er, M. | Taha, M.

4

Ligand Based Pharmacophore Modeling Followed by Biological Screening Lead to Discovery of Novel PDK1 Inhibitors as Anticancer Agents

enthalten in: Anti-cancer agents in medicinal chemistry | 2020

von Mansi, I. | Al-Sha'er, M. | Mhaidat, N. | +1

5

Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel Anti-PDK1 Hits

enthalten in: Medicinal chemistry (Shariqah (United Arab Emirates)) | 2020

von Mansi, I. | Al-Sha'er, M. | Mhaidat, N. | +2

6

Discovery of New Phosphoinositide 3-kinase Delta (PI3Kδ) Inhibitors via Virtual Screening using Crystallography-derived Pharmacophore Modelling and QSAR Analysis

enthalten in: Medicinal chemistry (Shariqah (United Arab Emirates)) | 2019

von Al-Sha'er, M. | Al-Aqtash, R. | Taha, M.

7

Ligand-based modeling of Akt3 lead to potent dual Akt1/Akt3 inhibitor

enthalten in: Journal of molecular graphics & modelling | 2018

von Al-Sha'er, M. | Taha, M.

8

Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation

enthalten in: Journal of enzyme inhibition and medicinal chemistry | 2016

von Al-Sha'er, M. | Mansi, I. | Khanfar, M. | +1

ErratumIn: J Enzyme Inhib Med Chem. 2016;31(sup4):x. - PMID 27978774

9

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

enthalten in: European journal of medicinal chemistry | 2014

von Taha, M. | Al-Sha'er, M. | Khanfar, M. | +1

10

Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

enthalten in: Journal of molecular modeling | 2014

von Al-Sha'er, M. | Khanfar, M. | Taha, M.