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topic_facet:"MAP Kinase Kinase 1"
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/vufind/Search/Results?lookfor=%2233E86K87QN%22&type=Subject&filter%5B%5D=topic_facet%3A%22MAP+Kinase+Kinase+1%22
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PubPharm (116)
1
Protein phosphatase 6 regulates trametinib sensitivity, a mitogen-activated protein kinase kinase (MEK) inhibitor, by regulating MEK1/2-ERK1/2 signaling in canine melanoma cells
enthalten in:
The Journal of veterinary medical science
| 2023
von
Yamamoto, M.
|
Fujiwara, N.
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2
Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma
enthalten in:
International journal of molecular sciences
| 2023
von
Krebs, F.
|
Moura, B.
|
Missiaglia, E.
| +7
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3
Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS) : an international, randomised, open-label, multicentre, phase 2/3 trial
enthalten in:
Lancet (London, England)
| 2022
von
Gershenson, D.
|
Miller, A.
|
Brady, W.
| +23
CommentIn: Lancet. 2022 Feb 5;399(10324):499-501. - PMID 35123677
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4
FGFR2 loss sensitizes MYCN-amplified neuroblastoma CHP134 cells to CHK1 inhibitor-induced apoptosis
enthalten in:
Cancer science
| 2022
von
Ando, K.
|
Ohira, M.
|
Takada, I.
| +8
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5
Lasting Complete Clinical Response of a Recurring Cutaneous Squamous Cell Carcinoma With MEK Mutation and PIK3CA Amplification Achieved by Dual Trametinib and Metformin Therapy
enthalten in:
JCO precision oncology
| 2022
von
Remenár, .
|
Dóczi, R.
|
Dirner, A.
| +13
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6
Molecular Management of Multifocal Atrial Tachycardia in Noonan's Syndrome With MEK1/2 Inhibitor Trametinib
enthalten in:
Circulation. Genomic and precision medicine
| 2021
von
Meisner, J.
|
Bradley, D.
|
Russell, M.
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7
Response to BRAF and MEK1/2 inhibition in a young adult with BRAF V600E mutant epithelioid glioblastoma multiforme : A Case Report and Literature Review
enthalten in:
Current problems in cancer
| 2021
von
Venkatesh, A.
|
Joshi, A.
|
Allinson, K.
| +6
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8
Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor-Resistant Melanoma
enthalten in:
Molecular cancer therapeutics
| 2021
von
Nassar, K.
|
Hintzsche, J.
|
Bagby, S.
| +8
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9
Dual Inhibition of DKC1 and MEK1/2 Synergistically Restrains the Growth of Colorectal Cancer Cells
enthalten in:
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
| 2021
von
Kan, G.
|
Wang, Z.
|
Sheng, C.
| +4
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10
Comment on : Langerhans cell histiocytosis with BRAF p.N486_P490del or MAP2K1 p.K57_G61del treated by the MEK inhibitor trametinib
enthalten in:
Pediatric blood & cancer
| 2021
von
Vicenzi, P.
|
Ray, A.
CommentOn: Pediatr Blood Cancer. 2020 Dec;67(12):e28712. - PMID 32991018
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Thema: MAP Kinase Kinase 1
Medienart
116
Aufsätze
114
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114
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Zeitschriftentitel
5
Clinical cancer research : an official journal ...
5
Pediatric blood & cancer
4
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4
International journal of oncology
4
Journal of clinical oncology : official journal...
4
Melanoma research
4
The Lancet. Oncology
4
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Oncotarget
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American journal of clinical dermatology
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Future oncology (London, England)
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Nature communications
2
The Journal of biological chemistry
Alle anzeigen ...
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Thema
116
33E86K87QN
116
EC 2.7.12.2
MAP Kinase Kinase 1
116
trametinib
115
Pyridones
115
Pyrimidinones
100
Journal Article
73
Protein Kinase Inhibitors
67
MAP2K1 protein, human
60
EC 2.7.11.1
52
MAP Kinase Kinase 2
50
Proto-Oncogene Proteins B-raf
46
Research Support, Non-U.S. Gov't
42
Antineoplastic Agents
37
BRAF protein, human
34
Imidazoles
34
Oximes
34
QGP4HA4G1B
34
dabrafenib
31
EC 2.7.1.-
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Erscheinungszeitraum
25
2020-
91
2010-2019
Erscheinungsjahr(e)
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Sprache
116
Englisch
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