Suchergebnisse - (Person:"Spalluto, Giampiero")

PubPharm (15)

1

Novel fluorescent antagonist as a molecular probe in A(3) adenosine receptor binding assays using flow cytometry

enthalten in: Biochemical pharmacology | 2012

von Kozma, E. | Kumar, T. | Federico, S. | +7

2

Therapeutic potential of A2 and A3 adenosine receptor : a review of novel patented ligands

enthalten in: Expert opinion on therapeutic patents | 2012

von Federico, S. | Spalluto, G.

3

Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists

enthalten in: Bioorganic & medicinal chemistry letters | 2011

von Cheong, S. | Federico, S. | Venkatesan, G. | +5

4

The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists : new insights into structure-affinity relationship and receptor-antagonist recognition

enthalten in: Journal of medicinal chemistry | 2010

von Cheong, S. | Dolzhenko, A. | Kachler, S. | +8

5

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists : A preliminary inspection of ligand-receptor recognition process

enthalten in: Bioorganic & medicinal chemistry | 2010

von Pastorin, G. | Federico, S. | Paoletta, S. | +8

6

Receptor-driven identification of novel human A₃ adenosine receptor antagonists as potential therapeutic agents

enthalten in: Methods in enzymology | 2010

von Paoletta, S. | Federico, S. | Spalluto, G. | +1

7

Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach : An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites

enthalten in: Bioorganic & medicinal chemistry | 2009

von Michielan, L. | Bolcato, C. | Federico, S. | +9

8

The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library : application to a lead optimization of a human A3 adenosine receptor antagonist

enthalten in: Bioorganic & medicinal chemistry | 2006

von Moro, S. | Bacilieri, M. | Cacciari, B. | +5

9

A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro

enthalten in: British journal of pharmacology | 2006

von Pugliese, A. | Coppi, E. | Spalluto, G. | +2

10

Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations

enthalten in: Journal of medicinal chemistry | 2006

von Pastorin, G. | Da Ros, T. | Bolcato, C. | +7