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PubPharm (121)
91
Phase 2 randomized study of bortezomib-melphalan-prednisone with or without siltuximab (anti-IL-6) in multiple myeloma
enthalten in:
Blood
| 2014
von
San-Miguel, J.
|
Bladé, J.
|
Shpilberg, O.
| +18
ErratumIn: Blood. 2014 Aug 14;124(7):1201
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92
A phase I/II, multiple-dose, dose-escalation study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with advanced solid tumors
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2014
von
Angevin, E.
|
Tabernero, J.
|
Elez, E.
| +19
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93
Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeys
enthalten in:
The AAPS journal
| 2014
von
Wang, W.
|
Wang, X.
|
Doddareddy, R.
| +4
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94
A novel approach to evaluate the pharmacokinetic biocomparability of a monoclonal antibody derived from two different cell lines using simultaneous crossover design
enthalten in:
The AAPS journal
| 2014
von
Han, C.
|
McIntosh, T.
|
Geist, B.
| +7
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95
Evaluation of the QTc prolongation potential of a monoclonal antibody, siltuximab, in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, or low-volume multiple myeloma
enthalten in:
Cancer chemotherapy and pharmacology
| 2014
von
Thomas, S.
|
Suvorov, A.
|
Noens, L.
| +10
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96
IL6 sensitizes prostate cancer to the antiproliferative effect of IFNα2 through IRF9
enthalten in:
Endocrine-related cancer
| 2013
von
Erb, H.
|
Langlechner, R.
|
Moser, P.
| +9
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97
First IL-6-blocking drug nears approval for rare blood disorder
enthalten in:
Nature medicine
| 2013
von
Williams, S.
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98
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells
enthalten in:
Cancer research
| 2013
von
Kroon, P.
|
Berry, P.
|
Stower, M.
| +9
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99
A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2013
von
Kurzrock, R.
|
Voorhees, P.
|
Casper, C.
| +14
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100
A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer
enthalten in:
Investigational new drugs
| 2013
von
Hudes, G.
|
Tagawa, S.
|
Whang, Y.
| +6
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Thema: T4H8FMA7IM
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Thema
T4H8FMA7IM
121
siltuximab
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Antibodies, Monoclonal
104
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Interleukin-6
42
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tocilizumab
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