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topic_facet:"Research Support, Non-U.S. Gov't"
topic_facet:"Cytochrome P-450 CYP3A"
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PubPharm (32)
1
Evaluation of the usefulness of plasma 4β-hydroxycholesterol concentration normalized by 4α-hydroxycholesterol for accurate CYP3A phenotyping
enthalten in:
Clinical and translational science
| 2024
von
Oda, A.
|
Suzuki, Y.
|
Sato, H.
| +12
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2
The effect of genetic variants in the transcription factor TSPYL family on the CYP3A4 mediated cyclosporine metabolism in kidney transplant patients
enthalten in:
Clinical and translational science
| 2024
von
Zhai, Q.
|
Moes, D.
|
van Gelder, T.
| +7
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3
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants
enthalten in:
Clinical and translational science
| 2024
von
Sawant-Basak, A.
|
Bergman, A.
|
Mancuso, J.
| +5
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4
Study of the ketohexokinase inhibitor PF-06835919 as a clinical cytochrome P450 3A inducer : Integrated use of oral midazolam and liquid biopsy
enthalten in:
Clinical and translational science
| 2024
von
Qiu, R.
|
Fonseca, K.
|
Bergman, A.
| +8
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5
Impact of CYP2D6 and CYP2B6 phenotypes on the response to tramadol in patients with acute post-surgical pain
enthalten in:
Clinical and translational science
| 2024
von
Casajús, A.
|
Zubiaur, P.
|
Alday, E.
| +11
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6
Protocol of the IntenSify-Trial : An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy
enthalten in:
Clinical and translational science
| 2023
von
Hohmann, N.
|
Sprick, M.
|
Pohl, M.
| +19
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7
Drug-drug interaction prediction of ziritaxestat using a physiologically based enzyme and transporter pharmacokinetic network interaction model
enthalten in:
Clinical and translational science
| 2023
von
Perrier, J.
|
Gualano, V.
|
Helmer, E.
| +3
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8
Effect of itraconazole and fluconazole on the pharmacokinetics of valemetostat : An open-label, phase I study in healthy subjects
enthalten in:
Clinical and translational science
| 2023
von
Tachibana, M.
|
Matsuki, S.
|
Maekawa, Y.
| +4
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9
Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients
enthalten in:
Clinical and translational science
| 2023
von
Alghamdi, A.
|
Seay, S.
|
Hooper, D.
| +5
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10
First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers
enthalten in:
Clinical and translational science
| 2023
von
Tang, F.
|
Kunder, R.
|
Chu, T.
| +16
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Thema: Research Support, Non-U.S. Gov't
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Thema: Cytochrome P-450 CYP3A
Medienart
32
Aufsätze
32
E-Artikel
32
E-Ressourcen
Zeitschriftentitel
32
Clinical and translational science
Thema
Cytochrome P-450 CYP3A
32
EC 1.14.14.1
32
Journal Article
Research Support, Non-U.S. Gov't
9
Midazolam
9
R60L0SM5BC
8
Cytochrome P-450 CYP3A Inhibitors
5
9035-51-2
5
CYP3A4 protein, human
5
Clinical Trial, Phase I
5
Cytochrome P-450 Enzyme System
5
EC 1.14.14.55
4
304NUG5GF4
4
Cytochrome P-450 CYP2C19
4
Itraconazole
4
Pharmaceutical Preparations
3
CYP3A protein, human
3
Cytochrome P-450 CYP2C9
3
Cytochrome P-450 CYP3A Inducers
3
EC 1.14.13.-
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Erscheinungszeitraum
5
2024
9
2023
11
2022
3
2021
4
2020
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Sprache
32
Englisch
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