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topic_facet:"Research Support, Non-U.S. Gov't"
publishDate:"[2000 TO 2009]"
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PubPharm (11)
1
Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
enthalten in:
Journal of medicinal chemistry
| 2009
von
Thompson, A.
|
Blaser, A.
|
Anderson, R.
| +5
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2
Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells
enthalten in:
Molecular cancer therapeutics
| 2009
von
Parsels, L.
|
Morgan, M.
|
Tanska, D.
| +8
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3
Intermediates in the reduction of the antituberculosis drug PA-824, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, in aqueous solution
enthalten in:
Organic & biomolecular chemistry
| 2008
von
Anderson, R.
|
Shinde, S.
|
Maroz, A.
| +3
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4
Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases
enthalten in:
European journal of medicinal chemistry
| 2008
von
Smaill, J.
|
Baker, E.
|
Booth, R.
| +13
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5
Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling
enthalten in:
Journal of medicinal chemistry
| 2007
von
Palmer, B.
|
Henare, K.
|
Woon, S.
| +5
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6
Thalidomide pharmacokinetics and metabolite formation in mice, rabbits, and multiple myeloma patients
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2004
von
Chung, F.
|
Lu, J.
|
Palmer, B.
| +5
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7
Aziridinyldinitrobenzamides : synthesis and structure-activity relationships for activation by E. coli nitroreductase
enthalten in:
Journal of medicinal chemistry
| 2004
von
Helsby, N.
|
Atwell, G.
|
Yang, S.
| +7
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8
Thalidomide metabolites in mice and patients with multiple myeloma
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2003
von
Lu, J.
|
Palmer, B.
|
Kestell, P.
| +4
CommentIn: Clin Cancer Res. 2003 Nov 1;9(14):5429; author reply 5429. - PMID 14614031
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9
Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2,4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862 : distinct mechanisms of bioreductive activation
enthalten in:
Chemical research in toxicology
| 2003
von
Helsby, N.
|
Wheeler, S.
|
Pruijn, F.
| +4
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10
Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
enthalten in:
Oncology research
| 2003
von
Chung, F.
|
Palmer, B.
|
Muller, G.
| +4
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Thema: Research Support, Non-U.S. Gov't
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Erscheinungsjahr: 2000-2009
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Journal of medicinal chemistry
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Clinical cancer research : an official journal ...
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Research Support, Non-U.S. Gov't
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0829J8133H
3
4Z8R6ORS6L
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Angiogenesis Inhibitors
3
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3
Thalidomide
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vadimezan
2
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Comparative Study
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EC 1.7.-
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NF-kappa B
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Nitroimidazoles
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Protein Kinase Inhibitors
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