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topic_facet:"Receptor, Adenosine A3"
topic_facet:"Pyrimidines"
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PubPharm (13)
1
1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines
enthalten in:
ChemMedChem
| 2023
von
Federico, S.
|
Persico, M.
|
Trevisan, L.
| +11
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2
Targeting G Protein-Coupled Receptors with Magnetic Carbon Nanotubes : The Case of the A3 Adenosine Receptor
enthalten in:
ChemMedChem
| 2020
von
Pineux, F.
|
Federico, S.
|
Klotz, K.
| +7
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3
1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists : Modifications at the 8 position to reach selectivity towards A3 adenosine receptor subtype
enthalten in:
European journal of medicinal chemistry
| 2018
von
Federico, S.
|
Margiotta, E.
|
Salmaso, V.
| +5
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4
Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5-c]pyrimidines to explore the antagonist profiling on adenosine receptors : a preliminary structure-activity relationship study
enthalten in:
Journal of medicinal chemistry
| 2014
von
Federico, S.
|
Ciancetta, A.
|
Porta, N.
| +6
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5
Exploring the directionality of 5-substitutions in a new series of 5-alkylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine as a strategy to design novel human a(3) adenosine receptor antagonists
enthalten in:
Journal of medicinal chemistry
| 2012
von
Federico, S.
|
Ciancetta, A.
|
Sabbadin, D.
| +6
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6
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach : An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites
enthalten in:
Bioorganic & medicinal chemistry
| 2009
von
Michielan, L.
|
Bolcato, C.
|
Federico, S.
| +9
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7
The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library : application to a lead optimization of a human A3 adenosine receptor antagonist
enthalten in:
Bioorganic & medicinal chemistry
| 2006
von
Moro, S.
|
Bacilieri, M.
|
Cacciari, B.
| +5
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8
Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigations
enthalten in:
Journal of medicinal chemistry
| 2006
von
Pastorin, G.
|
Da Ros, T.
|
Bolcato, C.
| +7
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9
Ligand-based homology modeling as attractive tool to inspect GPCR structural plasticity
enthalten in:
Current pharmaceutical design
| 2006
von
Moro, S.
|
Deflorian, F.
|
Bacilieri, M.
| +1
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10
Combined target-based and ligand-based drug design approach as a tool to define a novel 3D-pharmacophore model of human A3 adenosine receptor antagonists : pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as a key study
enthalten in:
Journal of medicinal chemistry
| 2005
von
Moro, S.
|
Braiuca, P.
|
Deflorian, F.
| +7
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Thema: Receptor, Adenosine A3
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Thema: Pyrimidines
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13
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Journal of medicinal chemistry
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Bioorganic & medicinal chemistry
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European journal of medicinal chemistry
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Thema
13
Journal Article
Pyrimidines
Receptor, Adenosine A3
11
Research Support, Non-U.S. Gov't
9
Triazoles
7
Purinergic P1 Receptor Antagonists
5
Adenosine A3 Receptor Antagonists
4
Pyrazoles
4
Receptors, Purinergic P1
3
Receptor, Adenosine A2A
2
9009-81-8
2
Cyclic AMP
2
E0399OZS9N
2
Ligands
2
Pyrazolotriazolopyrimidine
2
Rhodopsin
2
[1,2,4]triazolo[1,5-c]pyrimidine
1
1,2,4-triazolo(1,5-c)pyrimidine
1
35920-39-9
1
3QD5KJZ7ZJ
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Erscheinungszeitraum
2
2020-
3
2010-2019
8
2000-2009
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13
Englisch
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