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topic_facet:"Pyrimidines"
topic_facet:"Adenosine A2 Receptor Antagonists"
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PubPharm (4)
1
Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment
enthalten in:
PloS one
| 2018
von
Shao, Y.
|
Ma, X.
|
Paira, P.
| +11
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2
The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists : new insights into structure-affinity relationship and receptor-antagonist recognition
enthalten in:
Journal of medicinal chemistry
| 2010
von
Cheong, S.
|
Dolzhenko, A.
|
Kachler, S.
| +8
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3
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach : An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites
enthalten in:
Bioorganic & medicinal chemistry
| 2009
von
Michielan, L.
|
Bolcato, C.
|
Federico, S.
| +9
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4
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo-pyrimidine antagonists binding site of the human adenosine A2A receptor
enthalten in:
Journal of chemical information and modeling
| 2008
von
Michielan, L.
|
Bacilieri, M.
|
Schiesaro, A.
| +7
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1
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Bioorganic & medicinal chemistry
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Journal of chemical information and modeling
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PloS one
Thema
Adenosine A2 Receptor Antagonists
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Pyrimidines
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Research Support, Non-U.S. Gov't
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Pyrazoles
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Receptor, Adenosine A2A
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EC 4.6.1.1
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2010-2019
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