Suchergebnisse - (Person:"Curtin, Nicola")

PubPharm (47)

21

A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation

enthalten in: Cancer chemotherapy and pharmacology | 2013

von Plummer, R. | Lorigan, P. | Steven, N. | +10

22

Clinicopathological features of homologous recombination-deficient epithelial ovarian cancers : sensitivity to PARP inhibitors, platinum, and survival

enthalten in: Cancer research | 2012

von Mukhopadhyay, A. | Plummer, E. | Elattar, A. | +8

23

The clinically active PARP inhibitor AG014699 ameliorates cardiotoxicity but does not enhance the efficacy of doxorubicin, despite improving tumor perfusion and radiation response in mice

enthalten in: Molecular cancer therapeutics | 2011

von Ali, M. | Kamjoo, M. | Thomas, H. | +6

24

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

enthalten in: Nature medicine | 2011

von Johnson, N. | Li, Y. | Walton, Z. | +12

CommentIn: Nat Rev Clin Oncol. 2011 Sep;8(9):508. - PMID 21769119

25

Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2

enthalten in: Journal of the National Cancer Institute | 2011

von Drew, Y. | Mulligan, E. | Vong, W. | +9

26

The use of PARP inhibitors in cancer therapy : use as adjuvant with chemotherapy or radiotherapy; use as a single agent in susceptible patients; techniques used to identify susceptible patients

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2011

von Shall, S. | Gaymes, T. | Farzaneh, F. | +2

27

Strategies employed for the development of PARP inhibitors

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2011

von Canan, S. | Maegley, K. | Curtin, N.

28

Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials

enthalten in: Cancer chemotherapy and pharmacology | 2010

von Zaremba, T. | Thomas, H. | Cole, M. | +2

29

6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance

enthalten in: Cancer research | 2010

von Issaeva, N. | Thomas, H. | Djureinovic, T. | +18

ErratumIn: Cancer Res. 2010 Oct 1;70(19):7734 Djurenovic, Tatjana [corrected to Djureinovic, Tatjana]

30

Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2010

von Mukhopadhyay, A. | Elattar, A. | Cerbinskaite, A. | +7