Suchergebnisse - (Person:"Curtin, Nicola")

PubPharm (12)

1

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System

enthalten in: Molecular cancer therapeutics | 2015

von Parrish, K. | Cen, L. | Murray, J. | +11

2

A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation

enthalten in: Cancer chemotherapy and pharmacology | 2013

von Plummer, R. | Lorigan, P. | Steven, N. | +10

3

Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase : a contributory factor to chemopotentiation in vivo?

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Ali, M. | Telfer, B. | McCrudden, C. | +9

4

Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Daniel, R. | Rozanska, A. | Thomas, H. | +9

5

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

enthalten in: Molecular cancer therapeutics | 2007

von Thomas, H. | Calabrese, C. | Batey, M. | +9

6

PARP inhibitors for cancer therapy

enthalten in: Expert reviews in molecular medicine | 2005

von Curtin, N.

7

Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors

enthalten in: Bioorganic & medicinal chemistry letters | 2004

von White, A. | Curtin, N. | Eastman, B. | +9

8

Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2004

von Curtin, N. | Wang, L. | Yiakouvaki, A. | +8

9

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361

enthalten in: Journal of the National Cancer Institute | 2004

von Calabrese, C. | Almassy, R. | Barton, S. | +18

10

Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors : chemopotentiation and pharmacological studies

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2003

von Calabrese, C. | Batey, M. | Thomas, H. | +12