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topic_facet:"Phase: Phase 1"
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PubPharm (23.376)
71
This trial will evaluate the safety and efficacy of HepaStem compared to placebo in patients with a cirrhotic liver condition called Acute on Chronic Liver Failure (ACLF). The study will be performed in multiple centers and in a double-blinded manner, meaning neither the patients nor the treating physicians know who is on placebo or the study drug. : Randomized, placebo-controlled, double blind, multi-centre Phase IIb study to evaluate the efficacy and safety of HepaStem in patients with Acute on Chronic Liver Failure (ACLF) - DHELIVER - HEP102 - DHELIVER
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| 2023
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72
A Study of BMS-813160 in Combination with Chemotherapy or Nivolumab in Patients with Advanced Solid Tumors : A Phase 1b/2 Study of BMS-813160 in Combination with Chemotherapy or Nivolumab in Patients with Advanced Solid Tumors.
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| 2023
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73
A phase I-IIa clinical trial, evaluating the therapeutic vaccine hVEGF26-104/RFASE in patients with advanced cancer : A phase I- IIa open-label clinical trial, evaluating the therapeutic vaccine hVEGF26-104/RFASE in patients with advanced solid tumors
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| 2023
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74
Randomisierte, unverblindete, multizentrische klinische Prüfung der Phase I/II zum Vergleich einer Re-Bestrahlung plus einer Gabe von BIBF1120 gegenüber einer alleinigen Re-Bestrahlung zur Behandlung von Patienten mit erster oder zweiter Progression eines Glioblastoms : A phase I/II, randomized, open-label, multi-centre study of BIBF1120 +reirradiation (R-RT) versus reirradiation in the treatment of patients withfirst or second progression of glioblastoma - NOA-12: BIBF1120 and R-RT in glioblastoma
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| 2023
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75
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 1b/2a Study of WVE-120101 Administered Intrathecally in Patients with Huntington’s Disease : A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 1b/2a Study of WVE-120101 Administered Intrathecally in Patients with Huntington’s Disease
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| 2023
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76
A double-blinded, randomized, placebo-controlled phase I/IIa study in healthy subjects and patients with liver cirrhosis evaluating safety, pharmacokinetics and preliminary effect of single and multiple doses of GR3027. : Safety, tolerability and pharmacokinetics (PKs) of multiple oral doses of GR3027 in healthy male volunteers and single and multiple doses in patients with cirrhosis. Preliminary efficacy in cirrhotic patients with evidence of covert hepatic encephalopathy (CHE). A prospective, double-blinded, randomized, placebo-controlled phase I/IIa study.
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| 2023
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77
2-part study of DCR-PHXC in healthy volunteers and in primary hyperoxaluria patients : A Placebo-Controlled, Single-Blind, Single-Center Phase 1 Study in Normal Healthy Volunteers and Open-Label Multi Center Study in Patients with Primary Hyperoxaluria to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Doses of DCR PHXC Solution for Injection (subcutaneous use) - 2-part study of DCR-PHXC in NHV and PH patients
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| 2023
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78
MK-3475 (SCH 9000475) as neoadjuvant and adjuvant therapy in Stage III-IVA resectable LA HNSCC (Locoregionally Advanced Head and Neck Squamous Cell Carcinoma) : A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for StageIII-IVA Resectable Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA HNSCC) - MK-3475 (SCH 9000475) as neoadjuvant and adjuvant therapy in Stage III-IVA resectable LA HNSCC
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| 2023
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79
A study to evaluate the long-term safety of patients with advanced lymphoid malignancies who have been previously administered with UCART19 or ALLO-501 : Long-term follow-up study of patients who have previously been exposed to UCART19 / ALLO-501 (allogeneic engineered T-cells expressing a lentiviral-based anti-CD19 chimeric antigen receptor)
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| 2023
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80
A Phase I/II clinical study of IMA970A plus CV8102 and Cyclophosphamide for patients with liver cancer : A phase I/II trial of IMA970A plus CV8102 following a single pre-vaccination infusion of cyclophosphamide in patients with very early, early and intermediate stage of hepatocellular carcinoma after any standard treatments
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| 2023
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Thema: Phase: Phase 1
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WHO International Clinical Trials Registry Plat...
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Phase: Phase 1
21.248
Study Type: Interventional
8.476
Recruitment Status: Not yet recruiting
5.910
Recruitment Status: Completed
3.278
Recruitment Status: Authorised-recruitment may ...
3.166
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1.454
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1.114
Recruitment Status: Complete: follow-up complete
226
Medical Condition: ;Not Applicable
196
Recruitment Status: Active, not recruiting
182
Recruitment Status: Complete: follow-up continuing
180
Study Type: BA/BE
140
Recruitment Status: Closed to Recruitment of Pa...
124
Study Type: Relative factors research
120
Recruitment Status: Stopped early
92
Medical Condition: ;Diseases of the circulatory...
90
Study Type: Diagnostic test
82
Recruitment Status: Withdrawn
80
Medical Condition: ;Neoplasms
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