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topic_facet:"Phase: Phase 1"
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PubPharm (3.278)
71
Safety and efficacy of a bilateral, single injection of a genetically modified virus particle under the retina in adults and children with achromatopsia (an eye disease caused by a defect in the genetic material), investigated in a clinical trial. : Safety and efficacy of a bilateral single subretinal injection of rAAV.hCNGA3 in adult and minor patients with CNGA3-linked achromatopsia investigated in a randomized, wait list controlled, observer-masked trial
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| 2023
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72
A Trial to Determine The Safety and Efficacy of CC-92480 Alone and When Combined With Dexamethasone in People Who Have Myeloma That is Not Responsive After Treatment or Who Had Myeloma Which Has Returned After a Period of Treatment : A Phase 1/2 Multicenter, Open-label Study to Assess the Safety, Pharmacokinetics and Efficacy of CC-92480 Monotherapy and in Combination with Dexamethasone in Subjects with Relapsed and Refractory Multiple Myeloma
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| 2023
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73
A Single-and Multiple-dose Study of Tedizolid Phosphate in Pediatric Subjects Aged < 2 Years Old : A Phase 1, Single-and Multiple-Dose Safety and Pharmacokinetic Study of Oral and IV Tedizolid Phosphate (MK-1986) in Inpatients Under 2 Years Old - A Single-and Multiple-dose Study of Tedizolid Phosphate in Pediatric Subjects Aged < 2 Years Old
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74
Safety Study of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors : A Phase 1/2a Dose Escalation and Cohort Expansion Study of the Safety, Tolerability, and Efficacy of Anti-LAG-3 Monoclonal Antibody (BMS-986016) Administered Alone and in Combination with Anti-PD-1 Monoclonal Antibody (Nivolumab, BMS-936558) in Advanced Solid Tumors
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| 2023
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75
SAFETY AND PHARMACOKINETICS OF ODM-209 IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER OR ESTROGEN RECEPTOR-POSITIVE, HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2-NEGATIVE ADVANCED BREAST CANCER : SAFETY AND PHARMACOKINETICS OF ODM-209 IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER OR ESTROGEN RECEPTOR-POSITIVE, HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2-NEGATIVE ADVANCED BREAST CANCER - STESIDES
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76
A Trial to Determine the Recommended Dose, Dosing Pattern, Effectiveness and Safety of CC-92480 When Combined with Standard Treatments in Patients Who have Non-responsive or Recurrent Myeloma and in Patients Who Have Been Newly Diagnosed with Myeloma. : A Phase 1/2, Multicenter, Open-label, Study to Determine the Recommended Dose and Regimen, and Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination with Standard Treatments in Subjects with Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)
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77
A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab combined with Ipilimumab in Subjects with Advanced or Metastatic Solid Tumors : A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab combined with Ipilimumab in Subjects with Advanced or Metastatic Solid Tumors+ Protocol Amendment 14, site-specific, dated 26-Oct-2016 - CheckMate 032:CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 032
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78
A study to learn about the safety and efficacy of the study drug product CLDN6 CAR-T with/without the second study drug product CLDN6 RNA-LPX in patients with a specific type of advanced cancer that has reoccurred and does not respond to standard of care treatment. : Phase 1/2a, first-in-human, open-label, dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of CLDN6 CAR-T with or without CLDN6 RNA-LPX in patients with CLDN6-positive relapsed or refractory advanced solid tumors
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| 2023
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79
GEN1042 safety trial in patients with malignant solid tumors : A first-in-human, open-label, dose-escalation trial with expansion cohorts to evaluate safety of GEN1042 in subjects with malignant solid tumors
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80
Phase 1b/2 Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia : Phase 1b/2 Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia
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Thema: Phase: Phase 1
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Medical Condition: The ‘wet’ form of age-re...
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