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topic_facet:"Phase: Phase 1"
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PubPharm (3.278)
11
A Phase 1/2 Multicenter Study of KTE-X19 in Adult Subjects with Relapsed/Refractory Chronic Lymphocytic Leukemia. : Phase 1/2 Multicenter Study Evaluating the Safety and Efficacy of KTE-X19 in Adult Subjects with Relapsed/Refractory Chronic Lymphocytic Leukemia - ZUMA-8
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| 2023
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12
A Pharmacokinetic, Pharmacodynamic, and Safety Study of Etrolizumab Followed by Open-Label Extension and Safety Monitoring in Pediatric Patients From 4 Years to Less Than 18 Years of Age with Moderate to Severe Ulcerative Colitis or Moderate to Severe Crohn’s Disease : A PHASE I, OPEN–LABEL, RANDOMIZED, PHARMACOKINETIC, PHARMACODYNAMIC, AND SAFETY STUDY OF ETROLIZUMAB FOLLOWED BY OPEN–LABEL EXTENSION AND SAFETY MONITORING IN PEDIATRIC PATIENTS FROM 4 YEARS TO LESS THAN 18 YEARS OF AGE WITH MODERATE TO SEVERE ULCERATIVE COLITIS OR MODERATE TO SEVERE CROHN’S DISEASE
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| 2023
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13
Clinical Trial to evaluate the safety and efficacy of oral treatment with OST-122 in patients with moderate to severe ulcerative colitis : A Phase Ib/IIa, randomized, double blind, placebo controlled, multicenter clinical trial to evaluate the safety, pharmacokinetics and efficacy of oral treatment with OST-122 in patients with moderate to severe ulcerative colitis
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| 2023
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14
A study of the investigational drug MCLA-128 which is an antibody that isspecific to both HER2 and HER3 receptors that are associated with solidtumors : A Phase I/II Study of MCLA-128, a full length IgG1 Bispecific Antibody Targeting HER2 and HER3, in Patients with Solid Tumors
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| 2023
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15
First-in-human, open-label, dose-escalation trial with expansion cohorts to evaluate safety of GEN1029 in patients with malignant solid tumors : First-in-human, open-label, dose-escalation trial with expansion cohorts to evaluate safety of GEN1029 in patients with malignant solid tumors - GEN1029 Safety Trial in Patients With Malignant Solid Tumors
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| 2023
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16
Long-Term Evaluation of BIIB067 : An Extension Study to Assess the Long-Term Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB067 Administered to Previously Treated Adults with Amyotrophic Lateral Sclerosis Caused by Superoxide Dismutase 1 Mutation - Biogen 233AS102 Study of BIIB067 in Amyotrophic Lateral Sclerosis
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| 2023
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17
A study evaluating the safety and efficacy of ponatinib for the treatment of recurrent or refractory leukemias or solid tumors in children : An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias or Solid Tumors in Pediatric Participants
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| 2023
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18
A dose escalation trial to assess the safety and tolerability of multiple doses of the CAN04 antibody, in patients with solid malignant tumors. : An open label, dose escalation followed by dose expansion, safety and tolerability trial of CAN04, a fully humanized monoclonal antibody against IL1RAP, in subjects with solid malignant tumors - CANFOUR
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| 2023
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19
Study of ALRN-6924, for the Prevention of Topotecan-induced Myelosuppression During Treatment for Small Cell Lung Cancer : A Phase 1b/2 Study of the Dual MDMX/MDM2 Inhibitor, ALRN-6924, for the Prevention of Topotecan-induced Myelosuppression During Treatment for Small Cell Lung Cancer
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20
Long term continuous infusion ch14.18/CHO plus s.c. aldesleukin (IL-2) randomised : A PHASE I/II DOSE SCHEDULE FINDING STUDYFOR CH14.18/CHO CONTINUOUS INFUSION COMBINED WITH SUBCUTANEOUS ALDESLEUKIN (IL-2)IN PATIENTS WITH PRIMARY REFRACTORY OR RELAPSING NEUROBLASTOMA - Long term continuous infusion ch14.18/CHO
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| 2023
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Thema: Phase: Phase 1
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Medical Condition: Advanced Solid Tumors MedDRA...
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Medical Condition: The ‘wet’ form of age-re...
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Medical Condition: pediatric CD22-positive rela...
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Medical Condition: PMF or PPV- MF, or PET- MF M...
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Medical Condition: Pediatric patients with Phil...
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