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topic_facet:"HIV Reverse Transcriptase"
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PubPharm (10)
1
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains
enthalten in:
European journal of medicinal chemistry
| 2020
von
Nalli, M.
|
Armijos Rivera, J.
|
Masci, D.
| +14
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2
New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors
enthalten in:
European journal of medicinal chemistry
| 2014
von
Famiglini, V.
|
La Regina, G.
|
Coluccia, A.
| +10
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3
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors
enthalten in:
Journal of medicinal chemistry
| 2012
von
La Regina, G.
|
Coluccia, A.
|
Brancale, A.
| +11
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4
Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates
enthalten in:
Antiviral chemistry & chemotherapy
| 2011
von
Samuele, A.
|
Bisi, S.
|
Kataropoulou, A.
| +5
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5
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors : new cyclic substituents at indole-2-carboxamide
enthalten in:
Journal of medicinal chemistry
| 2011
von
La Regina, G.
|
Coluccia, A.
|
Brancale, A.
| +9
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6
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus
enthalten in:
Journal of medicinal chemistry
| 2009
von
Piscitelli, F.
|
Coluccia, A.
|
Brancale, A.
| +12
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7
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex
enthalten in:
Antiviral research
| 2009
von
Samuele, A.
|
Kataropoulou, A.
|
Viola, M.
| +5
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8
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors : role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity
enthalten in:
Journal of medicinal chemistry
| 2007
von
Regina, G.
|
Coluccia, A.
|
Piscitelli, F.
| +9
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9
Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors
enthalten in:
ChemMedChem
| 2006
von
Di Santo, R.
|
Costi, R.
|
Artico, M.
| +8
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10
High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme
enthalten in:
Antimicrobial agents and chemotherapy
| 2005
von
Cancio, R.
|
Silvestri, R.
|
Ragno, R.
| +8
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1
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Thema: HIV Reverse Transcriptase
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Thema
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EC 2.7.7.49
HIV Reverse Transcriptase
10
Journal Article
10
Reverse Transcriptase Inhibitors
Sulfones
9
Research Support, Non-U.S. Gov't
6
Indoles
5
Anti-HIV Agents
4
EC 2.7.7.-
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reverse transcriptase, Human immunodeficiency v...
2
AIDS
2
HIV-1
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Indolylarylsulfone
2
Reverse transcriptase
1
0C50HW4FO1
1
16079-88-2
1
4B9XT59T7S
1
6RGF96R053
1
8724FJW4M5
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99DK7FVK1H
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2020-
4
2010-2019
5
2000-2009
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