Suchergebnisse - (Person:"Maga, Giovanni")

PubPharm (16)

1

New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains

enthalten in: European journal of medicinal chemistry | 2020

von Nalli, M. | Armijos Rivera, J. | Masci, D. | +14

2

New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors

enthalten in: Journal of medicinal chemistry | 2012

von La Regina, G. | Coluccia, A. | Brancale, A. | +11

3

Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates

enthalten in: Antiviral chemistry & chemotherapy | 2011

von Samuele, A. | Bisi, S. | Kataropoulou, A. | +5

4

Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants

enthalten in: Bioorganic & medicinal chemistry letters | 2011

von Butini, S. | Gemma, S. | Brindisi, M. | +11

5

Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation

enthalten in: Antiviral research | 2010

von Samuele, A. | Crespan, E. | Vitellaro, S. | +4

6

Crystal structure of HIV-1 reverse transcriptase bound to a non-nucleoside inhibitor with a novel mechanism of action

enthalten in: Angewandte Chemie (International ed. in English) | 2010

von Freisz, S. | Bec, G. | Radi, M. | +7

7

Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

enthalten in: Bioorganic & medicinal chemistry | 2010

von Monforte, A. | Logoteta, P. | De Luca, L. | +6

8

Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations

enthalten in: Journal of medicinal chemistry | 2009

von Butini, S. | Brindisi, M. | Cosconati, S. | +15

9

Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants

enthalten in: Journal of medicinal chemistry | 2009

von Radi, M. | Maga, G. | Alongi, M. | +15

10

Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex

enthalten in: Antiviral research | 2009

von Samuele, A. | Kataropoulou, A. | Viola, M. | +5