Suchergebnisse - (Person:"Curtin, Nicola")

PubPharm (27)

11

Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies

enthalten in: Haematologica | 2013

von Gaymes, T. | Mohamedali, A. | Patterson, M. | +8

12

Visualization of a DNA-PK/PARP1 complex

enthalten in: Nucleic acids research | 2012

von Spagnolo, L. | Barbeau, J. | Curtin, N. | +2

13

Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers

enthalten in: The Biochemical journal | 2011

von Zaremba, T. | Thomas, H. | Cole, M. | +3

14

Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2

enthalten in: Journal of the National Cancer Institute | 2011

von Drew, Y. | Mulligan, E. | Vong, W. | +9

15

Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials

enthalten in: Cancer chemotherapy and pharmacology | 2010

von Zaremba, T. | Thomas, H. | Cole, M. | +2

16

Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2010

von Mukhopadhyay, A. | Elattar, A. | Cerbinskaite, A. | +7

17

Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation

enthalten in: International journal of radiation oncology, biology, physics | 2009

von Mitchell, J. | Smith, G. | Curtin, N.

18

Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Daniel, R. | Rozanska, A. | Thomas, H. | +9

19

Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines

enthalten in: Molecular cancer therapeutics | 2009

von Clarke, M. | Mulligan, E. | Grogan, P. | +9

20

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

enthalten in: Molecular cancer therapeutics | 2007

von Thomas, H. | Calabrese, C. | Batey, M. | +9