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topic_facet:"Clinical Trial, Phase I"
topic_facet:"EC 2.7.10.1"
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PubPharm (11)
1
Safety, efficacy and pharmacokinetics of BPI-9016M in c-MET overexpression or MET exon 14 skipping mutation patients with locally advanced or metastatic non-small-cell lung cancer : a phase Ib study
enthalten in:
BMC cancer
| 2023
von
Hu, X.
|
Cui, X.
|
Wang, Z.
| +16
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2
Conteltinib (CT-707) in patients with advanced ALK-positive non-small cell lung cancer : a multicenter, open-label, first-in-human phase 1 study
enthalten in:
BMC medicine
| 2022
von
Xing, P.
|
Zhao, Q.
|
Zhang, L.
| +5
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3
Safety, Efficacy, and Pharmacokinetics of Rezivertinib (BPI-7711) in Patients With Advanced NSCLC With EGFR T790M Mutation : A Phase 1 Dose-Escalation and Dose-Expansion Study
enthalten in:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
| 2022
von
Shi, Y.
|
Zhao, Y.
|
Yang, S.
| +19
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4
A phase I study of FCN-411, a pan-HER inhibitor, in EGFR-mutated advanced NSCLC after progression on EGFR tyrosine kinase inhibitors
enthalten in:
Lung cancer (Amsterdam, Netherlands)
| 2022
von
Lin, L.
|
Pan, H.
|
Li, X.
| +13
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5
Safety and activity of WX-0593 (Iruplinalkib) in patients with ALK- or ROS1-rearranged advanced non-small cell lung cancer : a phase 1 dose-escalation and dose-expansion trial
enthalten in:
Signal transduction and targeted therapy
| 2022
von
Shi, Y.
|
Fang, J.
|
Hao, X.
| +26
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6
Development of an LC-MS/MS method for quantifying ASK120067, a novel mutant-selective inhibitor of the epidermal growth factor receptor (EGFR) as well as its main metabolite in human plasma and its application in a pharmacokinetic study
enthalten in:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
| 2021
von
Cui, X.
|
Wang, S.
|
Gao, H.
| +5
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7
Phase 1/2 study of ceritinib in Chinese patients with advanced anaplastic lymphoma kinase-rearranged non-small cell lung cancer previously treated with crizotinib : Results from ASCEND-6
enthalten in:
Lung cancer (Amsterdam, Netherlands)
| 2020
von
Wu, Y.
|
Shi, Y.
|
Tan, D.
| +11
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8
Safety, Clinical Activity, and Pharmacokinetics of Alflutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
enthalten in:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
| 2020
von
Shi, Y.
|
Zhang, S.
|
Hu, X.
| +16
CommentIn: J Thorac Oncol. 2020 Jun;15(6):881-883. - PMID 32471561
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9
First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer
enthalten in:
Journal of hematology & oncology
| 2020
von
Hu, X.
|
Zheng, X.
|
Yang, S.
| +7
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10
Long-term effects of crizotinib in ALK-positive tumors (excluding NSCLC) : A phase 1b open-label study
enthalten in:
American journal of hematology
| 2018
von
Gambacorti-Passerini, C.
|
Orlov, S.
|
Zhang, L.
| +15
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Thema: Clinical Trial, Phase I
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Thema: EC 2.7.10.1
Medienart
11
Aufsätze
11
E-Artikel
11
E-Ressourcen
Zeitschriftentitel
2
Journal of thoracic oncology : official publica...
2
Lung cancer (Amsterdam, Netherlands)
1
American journal of hematology
1
BMC cancer
1
BMC medicine
1
Journal of chromatography. B, Analytical techno...
1
Journal of hematology & oncology
1
Signal transduction and targeted therapy
1
mAbs
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Thema
Clinical Trial, Phase I
EC 2.7.10.1
11
Journal Article
9
Research Support, Non-U.S. Gov't
8
Protein Kinase Inhibitors
5
Antineoplastic Agents
5
ErbB Receptors
5
Multicenter Study
5
Safety
4
Anaplastic Lymphoma Kinase
3
53AH36668S
3
Crizotinib
3
EGFR T790M mutation
3
EGFR protein, human
3
Efficacy
3
NSCLC
3
Pharmacokinetics
3
Tyrosine kinase inhibitor
2
Non-small cell lung cancer
2
Protein-Tyrosine Kinases
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Erscheinungszeitraum
9
2020-
2
2010-2019
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