Suchergebnisse - "Ding, Jian"

PubPharm (7)

1

Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors

enthalten in: European journal of medicinal chemistry | 2021

von Xiang, H. | Wang, X. | Chen, Y. | +12

2

The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8

enthalten in: Acta pharmacologica Sinica | 2018

von Shi, J. | Chen, S. | Guo, C. | +3

3

Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition

enthalten in: Cancer letters | 2017

von Sun, D. | Liu, H. | Dai, X. | +9

4

DW09849, a selective phosphatidylinositol 3-kinase (PI3K) inhibitor, prevents PI3K signaling and preferentially inhibits proliferation of cells containing the oncogenic mutation p110α (H1047R)

enthalten in: The Journal of pharmacology and experimental therapeutics | 2014

von Liu, J. | Gao, G. | Zhang, X. | +7

5

Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR

enthalten in: Biochemical pharmacology | 2012

von Chen, S. | Liu, J. | Wang, X. | +3

6

S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton

enthalten in: PloS one | 2009

von Zhang, C. | Yang, N. | Yang, C. | +9

7

Novel indole alpha-methylene-gamma-lactones as potent inhibitors for AKT-mTOR signaling pathway kinases

enthalten in: Bioorganic & medicinal chemistry letters | 2005

von Ding, H. | Zhang, C. | Wu, X. | +4

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