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topic_facet:"Antineoplastic Agents"
topic_facet:"TOR Serine-Threonine Kinases"
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PubPharm (10)
1
Alkaloid Derivative (Z)-3β-Ethylamino-Pregn-17(20)-en Inhibits Triple-Negative Breast Cancer Metastasis and Angiogenesis by Targeting HSP90α
enthalten in:
Molecules (Basel, Switzerland)
| 2022
von
Liu, X.
|
Wang, Y.
|
Zhang, X.
| +6
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2
Chamaejasmenin B, an Inhibitor for Metastatic Outgrowth, Reversed M2-Dominant Macrophage Polarization in Breast Tumor Microenvironment
enthalten in:
Frontiers in immunology
| 2021
von
Li, Q.
|
Sun, L.
|
Liu, L.
| +9
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3
Gomisin N Exerts Anti-liver Cancer Effects and Regulates PI3K-Akt and mTOR-ULK1 Pathways in Vitro
enthalten in:
Biological & pharmaceutical bulletin
| 2020
von
Zhu, P.
|
Lam, D.
|
Li, J.
| +11
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4
PTEN Expression, Not Mutation Status in TSC1, TSC2, or mTOR, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial
enthalten in:
Clinical cancer research : an official journal of the American Association for Cancer Research
| 2019
von
Voss, M.
|
Chen, D.
|
Reising, A.
| +12
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5
A novel hybrid of 3-benzyl coumarin seco-B-ring derivative and phenylsulfonylfuroxan induces apoptosis and autophagy in non-small-cell lung cancer
enthalten in:
Phytomedicine : international journal of phytotherapy and phytopharmacology
| 2019
von
Dong, M.
|
Ye, T.
|
Bi, Y.
| +7
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6
A hybrid of coumarin and phenylsulfonylfuroxan induces caspase-dependent apoptosis and cytoprotective autophagy in lung adenocarcinoma cells
enthalten in:
Phytomedicine : international journal of phytotherapy and phytopharmacology
| 2018
von
Wang, Q.
|
Guo, Y.
|
Jiang, S.
| +6
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7
Structure-based optimization leads to the discovery of NSC765844, a highly potent, less toxic and orally efficacious dual PI3K/mTOR inhibitor
enthalten in:
European journal of medicinal chemistry
| 2016
von
Han, J.
|
Chen, Y.
|
Yang, C.
| +7
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8
Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma
enthalten in:
Bioorganic & medicinal chemistry
| 2016
von
Chen, Y.
|
Zhang, L.
|
Yang, C.
| +7
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9
Genomic characterisation of two cancers of unknown primary cases supports a kidney cancer origin
enthalten in:
BMJ case reports
| 2015
von
Wei, E.
|
Chen, Y.
|
Hsieh, J.
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10
Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer
enthalten in:
BMC cancer
| 2010
von
Xu, D.
|
Geng, Q.
|
Tian, Y.
| +10
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1
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Thema: Antineoplastic Agents
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Thema: TOR Serine-Threonine Kinases
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Zeitschriftentitel
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Phytomedicine : international journal of phytot...
1
BMC cancer
1
BMJ case reports
1
Biological & pharmaceutical bulletin
1
Bioorganic & medicinal chemistry
1
Clinical cancer research : an official journal ...
1
European journal of medicinal chemistry
1
Frontiers in immunology
1
Molecules (Basel, Switzerland)
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Thema
Antineoplastic Agents
10
EC 2.7.11.1
10
Journal Article
TOR Serine-Threonine Kinases
6
EC 2.7.1.1
6
MTOR protein, human
5
Proto-Oncogene Proteins c-akt
4
Research Support, Non-U.S. Gov't
2
9HW64Q8G6G
2
Apoptosis
2
Autophagy
2
Biomarkers, Tumor
2
Coumarins
2
Dual inhibitors
2
Everolimus
2
Mammalian target of rapamycin (mTOR)
2
Oxadiazoles
2
Phenylsulfonylfuroxan
2
Phosphoinositide 3-kinase (PI3K)
2
Phosphoinositide-3 Kinase Inhibitors
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2020-
7
2010-2019
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