Suchergebnisse - (Person:"Spalluto, Giampiero")

PubPharm (105)

51

Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists

enthalten in: Bioorganic & medicinal chemistry letters | 2011

von Cheong, S. | Federico, S. | Venkatesan, G. | +5

52

Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility

enthalten in: Journal of medicinal chemistry | 2011

von Federico, S. | Paoletta, S. | Cheong, S. | +9

53

Pyrazolo derivatives as potent adenosine receptor antagonists : an overview on the structure-activity relationships

enthalten in: International journal of medicinal chemistry | 2011

von Cheong, S. | Venkatesan, G. | Paira, P. | +5

54

The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists : new insights into structure-affinity relationship and receptor-antagonist recognition

enthalten in: Journal of medicinal chemistry | 2010

von Cheong, S. | Dolzhenko, A. | Kachler, S. | +8

55

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists : A preliminary inspection of ligand-receptor recognition process

enthalten in: Bioorganic & medicinal chemistry | 2010

von Pastorin, G. | Federico, S. | Paoletta, S. | +8

56

Receptor-driven identification of novel human A₃ adenosine receptor antagonists as potential therapeutic agents

enthalten in: Methods in enzymology | 2010

von Paoletta, S. | Federico, S. | Spalluto, G. | +1

57

Exploring potency and selectivity receptor antagonist profiles using a multilabel classification approach : the human adenosine receptors as a key study

enthalten in: Journal of chemical information and modeling | 2009

von Michielan, L. | Stephanie, F. | Terfloth, L. | +6

58

Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach : An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites

enthalten in: Bioorganic & medicinal chemistry | 2009

von Michielan, L. | Bolcato, C. | Federico, S. | +9

59

6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors

enthalten in: Bioorganic & medicinal chemistry | 2009

von Crepaldi, P. | Cacciari, B. | Bonache, M. | +8

60

Human A3 adenosine receptor as versatile G protein-coupled receptor example to validate the receptor homology modeling technology

enthalten in: Current pharmaceutical design | 2009

von Morizzo, E. | Federico, S. | Spalluto, G. | +1