Suchergebnisse - "Spiekermann, Karsten"

PubPharm (9)

1

A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy

enthalten in: Annals of hematology | 2023

von Berdel, A. | Koch, R. | Gerss, J. | +15

2

A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia

enthalten in: European journal of medicinal chemistry | 2020

von Sellmer, A. | Pilsl, B. | Beyer, M. | +13

3

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

enthalten in: Nature medicine | 2017

von Göllner, S. | Oellerich, T. | Agrawal-Singh, S. | +25

4

Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors

enthalten in: Molecular cancer therapeutics | 2012

von Pietschmann, K. | Bolck, H. | Buchwald, M. | +7

5

Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells

enthalten in: Blood | 2004

von Bagrintseva, K. | Schwab, R. | Kohl, T. | +5

6

Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2003

von Spiekermann, K. | Bagrintseva, K. | Schwab, R. | +2

7

The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3

enthalten in: Blood | 2003

von Spiekermann, K. | Dirschinger, R. | Schwab, R. | +7

8

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia

enthalten in: Blood | 2002

von Spiekermann, K. | Bagrintseva, K. | Schoch, C. | +3

9

The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells

enthalten in: Experimental hematology | 2002

von Spiekermann, K. | Faber, F. | Voswinckel, R. | +1

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