Suchergebnisse - "IgG"

PubPharm (15)

1

Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo

enthalten in: mAbs | 2021

von Mester, S. | Evers, M. | Meyer, S. | +5

2

Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice

enthalten in: mAbs | 2020

von Low, B. | Christianson, G. | Lowell, E. | +2

3

Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life

enthalten in: mAbs | 2019

von Mackness, B. | Jaworski, J. | Boudanova, E. | +9

4

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

enthalten in: mAbs | 2019

von Challa, D. | Wang, X. | Montoyo, H. | +3

5

Effects of the FcRn developmental pharmacology on the pharmacokinetics of therapeutic monoclonal IgG antibody in pediatric subjects using minimal physiologically-based pharmacokinetic modelling

enthalten in: mAbs | 2018

von Hardiansyah, D. | Ng, C.

6

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration

enthalten in: mAbs | 2018

von Smith, B. | Kiessling, A. | Lledo-Garcia, R. | +21

7

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

enthalten in: mAbs | 2018

von Piche-Nicholas, N. | Avery, L. | King, A. | +5

8

Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

enthalten in: mAbs | 2016

von Avery, L. | Wang, M. | Kavosi, M. | +12

9

A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life

enthalten in: mAbs | 2015

von Souders, C. | Nelson, S. | Wang, Y. | +3

10

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity

enthalten in: mAbs | 2015

von Abdiche, Y. | Yeung, Y. | Chaparro-Riggers, J. | +9