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journalStr:"Xenobiotica"
topic_facet:"hepatocytes"
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PubPharm (17)
1
The common indoor air pollutant α-pinene is metabolised to a genotoxic metabolite α-pinene oxide
enthalten in:
Xenobiotica
| 2022
von
Waidyanatha, S.
|
Black, S.
|
Witt, K.
| +7
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2
Characterisation of intravenous pharmacokinetics in Göttingen minipig and clearance prediction using establishedin vitrotoin vivoextrapolation methodologies
enthalten in:
Xenobiotica
| 2022
von
Langthaler, K.
|
Jones, C.
|
Christensen, R.
| +3
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3
Characterisation of seven medications approved for attention-deficit/hyperactivity disorder usingin vitromodels of hepatic metabolism
enthalten in:
Xenobiotica
| 2022
von
Law, R.
|
Lewis, D.
|
Hain, D.
| +9
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4
Use of selective substrates and inhibitors to rapidly characterise batches of cryopreserved primary human hepatocytes for assessment of active uptake liability in drug discovery and development
enthalten in:
Xenobiotica
| 2022
von
Golding, M.
|
Light, O.
|
Williamson, B.
| +1
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5
Non-specific binding of compounds inin vitrometabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models
enthalten in:
Xenobiotica
| 2022
von
Gardner, I.
|
Xu, M.
|
Han, C.
| +11
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6
Kinetics of metabolism of deltamethrin andcis- andtrans-permethrinin vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol
enthalten in:
Xenobiotica
| 2021
von
Price, R.
|
Scott, M.
|
Cantrill, C.
| +8
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7
Main contribution of UGT1A1 and CYP2C9 in the metabolism of UR-1102, a novel agent for the treatment of gout
enthalten in:
Xenobiotica
| 2021
von
Yamane, M.
|
Igarashi, F.
|
Yamauchi, T.
| +1
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8
In vitrometabolism of HMTD and blood stability and toxicity of peroxide explosives (TATP and HMTD) in canines and humans
enthalten in:
Xenobiotica
| 2021
von
Gonsalves, M.
|
McLennan, L.
|
Slitt, A.
| +2
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9
Numerical analysis of time-dependent inhibition kinetics: comparison between rat liver microsomes and rat hepatocyte data for mechanistic model fitting
enthalten in:
Xenobiotica
| 2020
von
Pham, C.
|
Nagar, S.
|
Korzekwa, K.
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10
Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism
enthalten in:
Xenobiotica
| 2020
von
Sanoh, S.
|
Naritomi, Y.
|
Kitamura, S.
| +4
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Zeitschrift: Xenobiotica
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Thema: hepatocytes
Medienart
17
Aufsätze
17
E-Artikel
17
E-Ressourcen
Zeitschriftentitel
Xenobiotica
Thema
hepatocytes
5
liver microsomes
3
metabolism
3
pharmacokinetics
2
cytochrome P450
2
metabolic pathway
1
14C human
1
14C-labeled compounds
1
2-ethylhexyl-p-methoxycinnamate
1
ADHD
1
Alectinib
1
CYP2C33
1
CYP3A
1
Chimeric mice with humanized liver
1
Cytochrome P450
1
Deltamethrin
1
Disposition
1
Drug-metabolizing enzymes
1
Göttingen minipig pharmacokinetics
1
Hu-Liver cell
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Erscheinungszeitraum
10
2020-
7
2010-2019
Erscheinungsjahr(e)
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Sprache
17
Englisch
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