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journalStr:"Journal of medicinal chemistry"
topic_facet:"NS-5 protein, hepatitis C virus"
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PubPharm (64)
1
Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530)
enthalten in:
Journal of medicinal chemistry
| 2020
von
Randolph, J.
|
Voight, E.
|
Greszler, S.
| +7
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2
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues : Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C
enthalten in:
Journal of medicinal chemistry
| 2020
von
Wang, G.
|
Dyatkina, N.
|
Prhavc, M.
| +18
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3
Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor
enthalten in:
Journal of medicinal chemistry
| 2020
von
Liu, B.
|
Gai, K.
|
Qin, H.
| +12
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4
GSK2818713, a Novel Biphenylene Scaffold-Based Hepatitis C NS5A Replication Complex Inhibitor with Broad Genotype Coverage
enthalten in:
Journal of medicinal chemistry
| 2020
von
Kazmierski, W.
|
Baskaran, S.
|
Walker, J.
| +10
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5
Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate
enthalten in:
Journal of medicinal chemistry
| 2019
von
Ramdas, V.
|
Talwar, R.
|
Banerjee, M.
| +27
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6
Synthesis and Anti-HCV Activities of 4'-Fluoro-2'-Substituted Uridine Triphosphates and Nucleotide Prodrugs : Discovery of 4'-Fluoro-2'- C-methyluridine 5'-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection
enthalten in:
Journal of medicinal chemistry
| 2019
von
Wang, G.
|
Dyatkina, N.
|
Prhavc, M.
| +18
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7
Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus
enthalten in:
Journal of medicinal chemistry
| 2019
von
Mengshetti, S.
|
Zhou, L.
|
Sari, O.
| +22
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8
Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Substitutions
enthalten in:
Journal of medicinal chemistry
| 2018
von
Yu, W.
|
Tong, L.
|
Selyutin, O.
| +22
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9
Discovery of Novel Nucleotide Prodrugs with Improved Potency Against HCV Variants Carrying NS5B S282T Mutation
enthalten in:
Journal of medicinal chemistry
| 2017
von
Zhen, L.
|
Dai, L.
|
Wen, X.
| +8
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10
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture
enthalten in:
Journal of medicinal chemistry
| 2017
von
Zhou, S.
|
Mahmoud, S.
|
Liu, P.
| +16
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Zeitschrift: Journal of medicinal chemistry
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Thema: NS-5 protein, hepatitis C virus
Medienart
64
Aufsätze
51
E-Artikel
51
E-Ressourcen
13
Gedruckte Aufsätze
Zeitschriftentitel
Journal of medicinal chemistry
Thema
64
Antiviral Agents
64
EC 2.7.7.48
64
Journal Article
NS-5 protein, hepatitis C virus
64
Viral Nonstructural Proteins
21
Enzyme Inhibitors
13
Prodrugs
13
RNA-Dependent RNA Polymerase
12
Research Support, Non-U.S. Gov't
9
Indoles
8
Research Support, N.I.H., Extramural
7
Pyrrolidines
6
RNA, Viral
5
Benzimidazoles
5
Carbamates
5
Imidazoles
5
Nucleosides
5
Research Support, U.S. Gov't, Non-P.H.S.
5
Sulfonamides
4
HG18B9YRS7
Alle anzeigen ...
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Erscheinungszeitraum
4
2020-
45
2010-2019
15
2000-2009
Erscheinungsjahr(e)
Von:
Bis:
Sprache
64
Englisch
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