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PubPharm (127)
81
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
enthalten in:
Breast cancer research
| 2013
von
Eccles, S.
|
Aboagye, E.
|
Ali, S.
| +84
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82
Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies
enthalten in:
Haematologica
| 2013
von
Gaymes, T.
|
Mohamedali, A.
|
Patterson, M.
| +8
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83
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity
enthalten in:
Journal of medicinal chemistry
| 2013
von
Cano, C.
|
Saravanan, K.
|
Bailey, C.
| +14
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84
Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer
enthalten in:
Molecular cancer therapeutics
| 2013
von
Batey, M.
|
Zhao, Y.
|
Kyle, S.
| +6
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85
A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
enthalten in:
Cancer chemotherapy and pharmacology
| 2013
von
Plummer, R.
|
Lorigan, P.
|
Steven, N.
| +10
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86
A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
enthalten in:
Cancer chemotherapy and pharmacology
| 2013
von
Plummer, R.
|
Lorigan, P.
|
Steven, N.
| +10
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87
A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
enthalten in:
Cancer chemotherapy and pharmacology
| 2013
von
Plummer, R.
|
Lorigan, P.
|
Steven, N.
| +10
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88
DNA repair dysregulation from cancer driver to therapeutic target
enthalten in:
Nature reviews. Cancer
| 2012
von
Curtin, N.
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89
Clinicopathological features of homologous recombination-deficient epithelial ovarian cancers : sensitivity to PARP inhibitors, platinum, and survival
enthalten in:
Cancer research
| 2012
von
Mukhopadhyay, A.
|
Plummer, E.
|
Elattar, A.
| +8
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90
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K
enthalten in:
Molecular cancer therapeutics
| 2012
von
Munck, J.
|
Batey, M.
|
Zhao, Y.
| +15
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Cancers
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Oncotarget
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Breast cancer research and treatment
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Thema
100
Journal Article
51
Research Support, Non-U.S. Gov't
36
Poly(ADP-ribose) Polymerase Inhibitors
27
Antineoplastic Agents
22
EC 2.4.2.30
22
EC 2.7.11.1
19
Poly(ADP-ribose) Polymerases
19
Review
19
rucaparib
18
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17
8237F3U7EH
13
ATR
13
Enzyme Inhibitors
13
Protein Kinase Inhibitors
12
Ataxia Telangiectasia Mutated Proteins
12
DNA-Activated Protein Kinase
11
Poly (ADP-Ribose) Polymerase-1
10
PARP
9
Doxorubicin
9
PARP1 protein, human
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2020-
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2010-2019
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