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format_facet:"Elektronische Ressource"
topic_facet:"Pyrimidines"
topic_facet:"EC 1.14.14.1"
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PubPharm (10)
1
Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations : An Example Using Tofacitinib
enthalten in:
Journal of clinical pharmacology
| 2020
von
Tse, S.
|
Dowty, M.
|
Menon, S.
| +2
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2
Assessment of Clinical Drug-Drug Interactions of Elagolix, a Gonadotropin-Releasing Hormone Receptor Antagonist
enthalten in:
Journal of clinical pharmacology
| 2020
von
Polepally, A.
|
Ng, J.
|
Salem, A.
| +6
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3
An Open-Label Study to Assess the Effect of Itraconazole and Rifampin on Parsaclisib Pharmacokinetics When Administered Orally in Healthy Participants
enthalten in:
Journal of clinical pharmacology
| 2020
von
Li, J.
|
Rockich, K.
|
Yuska, B.
| +5
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4
Pharmacokinetics of tofacitinib, a janus kinase inhibitor, in patients with impaired renal function and end-stage renal disease
enthalten in:
Journal of clinical pharmacology
| 2014
von
Krishnaswami, S.
|
Chow, V.
|
Boy, M.
| +2
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5
A model-based approach to characterize the population pharmacokinetics and the relationship between the pharmacokinetic and safety profiles of RBP-7000, a new, long-acting, sustained-released formulation of risperidone
enthalten in:
Journal of clinical pharmacology
| 2013
von
Gomeni, R.
|
Heidbreder, C.
|
Fudala, P.
| +1
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6
Pharmacokinetics and short-term safety of etravirine in combination with fluconazole or voriconazole in HIV-negative volunteers
enthalten in:
Journal of clinical pharmacology
| 2013
von
Kakuda, T.
|
Van Solingen-Ristea, R.
|
Aharchi, F.
| +5
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7
The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers
enthalten in:
Journal of clinical pharmacology
| 2012
von
Shi, J.
|
Chen, X.
|
Emm, T.
| +8
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8
Effects of rifampin and ketoconazole on the pharmacokinetics of nilotinib in healthy participants
enthalten in:
Journal of clinical pharmacology
| 2011
von
Tanaka, C.
|
Yin, O.
|
Smith, T.
| +5
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9
Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety
enthalten in:
Journal of clinical pharmacology
| 2010
von
Xiang, Q.
|
Zhao, X.
|
Zhou, Y.
| +2
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10
CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole
enthalten in:
Journal of clinical pharmacology
| 2009
von
Weiss, J.
|
Ten Hoevel, M.
|
Burhenne, J.
| +5
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1
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Thema: Pyrimidines
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Thema: EC 1.14.14.1
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10
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10
E-Artikel
E-Ressourcen
Zeitschriftentitel
10
Journal of clinical pharmacology
Thema
EC 1.14.14.1
10
Journal Article
Pyrimidines
8
Cytochrome P-450 CYP3A
7
Research Support, Non-U.S. Gov't
5
CYP3A4 protein, human
5
EC 1.14.14.55
4
CYP2C19 protein, human
4
Cytochrome P-450 CYP2C19
4
Protein Kinase Inhibitors
3
ATP Binding Cassette Transporter, Subfamily B, ...
3
Aryl Hydrocarbon Hydroxylases
3
Clinical Trial, Phase I
3
Cytochrome P-450 CYP3A Inhibitors
3
Rifampin
3
VJT6J7R4TR
2
87LA6FU830
2
Antifungal Agents
2
Antipsychotic Agents
2
CYP2C9 protein, human
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