Suchergebnisse - "Curtin, Nicola"

PubPharm (11)

1

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers

enthalten in: Cancer discovery | 2017

von de Bono, J. | Ramanathan, R. | Mina, L. | +13

2

Strategies Employed for the Development of PARP Inhibitors

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2017

von Canan, S. | Maegley, K. | Curtin, N.

3

PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia

enthalten in: Oncotarget | 2015

von Herriott, A. | Tudhope, S. | Junge, G. | +13

4

Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself

enthalten in: PloS one | 2015

von McCrudden, C. | O'Rourke, M. | Cherry, K. | +14

5

PARP inhibitors for anticancer therapy

enthalten in: Biochemical Society transactions | 2014

von Curtin, N.

6

Visualization of a DNA-PK/PARP1 complex

enthalten in: Nucleic acids research | 2012

von Spagnolo, L. | Barbeau, J. | Curtin, N. | +2

7

Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers

enthalten in: The Biochemical journal | 2011

von Zaremba, T. | Thomas, H. | Cole, M. | +3

8

Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials

enthalten in: Cancer chemotherapy and pharmacology | 2010

von Zaremba, T. | Thomas, H. | Cole, M. | +2

9

Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation

enthalten in: International journal of radiation oncology, biology, physics | 2009

von Mitchell, J. | Smith, G. | Curtin, N.

10

Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma

enthalten in: Clinical cancer research : an official journal of the American Association for Cancer Research | 2009

von Daniel, R. | Rozanska, A. | Thomas, H. | +9