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PubPharm (3.374)
1
Long term continuous infusion ch14.18/CHO plus s.c. aldesleukin (IL-2) randomised : A PHASE I/II DOSE SCHEDULE FINDING STUDYFOR CH14.18/CHO CONTINUOUS INFUSION COMBINED WITH SUBCUTANEOUS ALDESLEUKIN (IL-2)IN PATIENTS WITH PRIMARY REFRACTORY OR RELAPSING NEUROBLASTOMA - Long term continuous infusion ch14.18/CHO
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| 2023
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2
A PHASE 3, DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED, PARALLEL GROUP, 27 WEEK TRIAL TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF TWO FIXED DOSES OF TAVAPADON IN EARLY PARKINSON’S DISEASE (TEMPO-1 TRIAL) : A PHASE 3, DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED, PARALLEL GROUP, 27 WEEK TRIAL TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF TWO FIXED DOSES OF TAVAPADON IN EARLY PARKINSON’S DISEASE (TEMPO-1 TRIAL)
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| 2023
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3
89Zirconium-labelled girentuximab (89Zr-TLX250) is a new diagnostic imaging agent which has a radionuclide (zirconium-89) linked with a drug known as girentuximab. The drug is known to be taken up by clear cell renal cell carcinoma. This product would be administered and then a scan of the body made by a PET/CT machine. This study is to determine the ability of the administered zirconium-89 girentuximab to correctly identify the nature of the known or suspected cancer within your kidney. : A confirmatory, prospective, open-label, multi-centre phase 3 study to evaluate diagnostic performance of 89Zirconium-labelled girentuximab(89Zr-TLX250) to non-invasively detect clear cell renal cell carcinoma (ccRCC) by positron emission tomography/CT (PET/CT) imaging in patients with indeterminate renal masses (ZIRCON study) - 89Zr-TLX250 for PET/CT imaging of ccRCC
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| 2023
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4
BI 425809 in patients with cognitive impairment due to Alzheimer's Disease. : A multi-centre, double-blind, parallel-group, randomised controlled study to investigate efficacy and safety of orally administered BI 425809 during a 12-week treatment period compared to placebo in patients with cognitive impairment due to Alzheimer´s Disease.
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| 2023
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5
Afatinib as Cancer therapy for Exocrine Pancreatic Tumours : Gemcitabine in Combination with the Oral Irreversible ErbB Inhibitor Afatinib versus Gemcitabine Alone in Patients with Metastatic Pancreatic Cancer: an Explorative Randomized Phase II Trial - Afatinib as Cancer therapy for Exocrine Pancreatic Tumours
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| 2023
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6
Atezolizumab, Pertuzumab and Trastuzumab with chemotherapy as neoadjuvant (before surgery) treatment of HER2 positive early high-risk and locally advanced breast cancer. : Atezolizumab, Pertuzumab and Trastuzumab with chemotherapy as neoadjuvant treatment of HER2 positive early high-risk and locally advanced breast cancer. - APTneo
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| 2023
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7
A clinical study with macimorelin acetate comparing three doses in their safety and tolerability in children with suspected growth hormone deficiency (GHD) : Open label, group comparison, dose escalation trial to investigate safety, tolerability, pharmacokinetics and pharmacodynamics of macimorelin acetate after single oral dosing of 0.25 mg/kg, 0.5 mg/kg, and 1 mg/kg in pediatric patients with suspected growth hormone deficiency (GHD)
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| 2023
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8
Controlled clinical trial to evaluate the efficacy and safety of MYRRHINIL-INTEST® versus placebo in patients with diarrhea-dominant irritable bowel syndrome (IBS-D) and patients with mixed-type irritable bowel syndrome (IBS-M) : Controlled clinical trial to evaluate the efficacy and safety of MYRRHINIL-INTEST® versus placebo in patients with diarrhea-dominant irritable bowel syndrome (IBS-D) and patients with mixed-type irritable bowel syndrome (IBS-M) - MYNIBOS
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| 2023
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9
EFICACY AND TOLERABILITY OF TWO REDUCED VOLUME PRODUCTS FOR COLORRECTAL CANCER SCREENING COLONOSCOPY: A COMPARATIVE, PARALLEL RANDOMIZED CLINICAL TRIAL. LOWOL STUDY. : EFICACY AND TOLERABILITY OF TWO REDUCED VOLUME PRODUCTS FOR COLORRECTAL CANCER SCREENING COLONOSCOPY: A COMPARATIVE, PARALLEL RANDOMIZED CLINICAL TRIAL. LOWOL STUDY. - LOWOL-19
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| 2023
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10
Long term continuous infusion ch14.18/CHO plus s.c. aldesleukin (IL-2) randomised : A PHASE I/II DOSE SCHEDULE FINDING STUDYFOR CH14.18/CHO CONTINUOUS INFUSION COMBINED WITH SUBCUTANEOUS ALDESLEUKIN (IL-2)IN PATIENTS WITH PRIMARY REFRACTORY OR RELAPSING NEUROBLASTOMA - Long term continuous infusion ch14.18/CHO
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| 2023
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