Suchergebnisse - "Curtin, Nicola"

PubPharm (121)

91

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

enthalten in: Nature medicine | 2011

von Johnson, N. | Li, Y. | Walton, Z. | +12

CommentIn: Nat Rev Clin Oncol. 2011 Sep;8(9):508. - PMID 21769119

92

Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers

enthalten in: The Biochemical journal | 2011

von Zaremba, T. | Thomas, H. | Cole, M. | +3

93

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination

enthalten in: Cancer chemotherapy and pharmacology | 2011

von Tavecchio, M. | Munck, J. | Cano, C. | +2

94

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination

enthalten in: Cancer chemotherapy and pharmacology | 2011

von Tavecchio, M. | Munck, J. | Cano, C. | +2

95

Nucleoside transport inhibitors : structure-activity relationships for pyrimido[5,4-d]pyrimidine derivatives that potentiate pemetrexed cytotoxicity in the presence of α1-acid glycoprotein

enthalten in: Journal of medicinal chemistry | 2011

von Saravanan, K. | Barlow, H. | Barton, M. | +7

96

Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2

enthalten in: Journal of the National Cancer Institute | 2011

von Drew, Y. | Mulligan, E. | Vong, W. | +9

97

The use of PARP inhibitors in cancer therapy : use as adjuvant with chemotherapy or radiotherapy; use as a single agent in susceptible patients; techniques used to identify susceptible patients

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2011

von Shall, S. | Gaymes, T. | Farzaneh, F. | +2

98

Strategies employed for the development of PARP inhibitors

enthalten in: Methods in molecular biology (Clifton, N.J.) | 2011

von Canan, S. | Maegley, K. | Curtin, N.

99

Targeting the DNA double strand break repair machinery in prostate cancer

enthalten in: PloS one | 2011

von Shaheen, F. | Znojek, P. | Fisher, A. | +7

100

DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype

enthalten in: Journal of medicinal chemistry | 2010

von Cano, C. | Barbeau, O. | Bailey, C. | +14

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