Suchergebnisse - "Curtin, Nicola"

PubPharm (218)

61

Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis: Mechanism and Potential Role for PARP Inhibitors

enthalten in: International journal of gynecological cancer | 2016

von Kotsopoulos, I. | Kucukmetin, A. | Mukhopadhyay, A. | +2

62

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer

enthalten in: The British journal of cancer | 2016

von Drew, Y. | Ledermann, J. | Hall, G. | +14

63

Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity

enthalten in: International journal of gynecological cancer | 2016

von O’Donnell, R. | Kaufmann, A. | Woodhouse, L. | +4

64

Imagestream detection and characterisation of circulating tumour cells – A liquid biopsy for hepatocellular carcinoma?

enthalten in: Journal of hepatology | 2016

von Ogle, L. | Orr, J. | Willoughby, C. | +7

65

Ovarian Cancers Harbor Defects in Nonhomologous End Joining Resulting in Resistance to Rucaparib

enthalten in: Clinical cancer research | 2016

von McCormick, A. | Donoghue, P. | Dixon, M. | +6

66

PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia

enthalten in: Oncotarget | 2015

von Herriott, A. | Tudhope, S. | Junge, G. | +13

67

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System

enthalten in: Molecular cancer therapeutics | 2015

von Parrish, K. | Cen, L. | Murray, J. | +11

68

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

enthalten in: Oncotarget | 2015

von Middleton, F. | Patterson, M. | Elstob, C. | +9

69

PARP activity in peripheral blood lymphocytes as a predictive biomarker for PARP inhibition in tumor tissues - A population pharmacokinetic/pharmacodynamic analysis of rucaparib

enthalten in: Clinical pharmacology in drug development | 2015

von Wang, D. | Li, C. | Sun, W. | +7

70

Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer

enthalten in: Molecular oncology | 2015

von Abdel-Fatah, T. | Middleton, F. | Arora, A. | +12