Suchergebnisse - (Person:"Spalluto, Giampiero")

PubPharm (183)

61

Does the combination of optimal substitutions at the C²-, N⁵- and N⁸-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A₃ adenosine receptors?

enthalten in: Bioorganic & medicinal chemistry | 2011

von Cheong, S. | Dolzhenko, A. | Paoletta, S. | +8

62

Does the combination of optimal substitutions at the C2-, N5- and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors?

enthalten in: Bioorganic & medicinal chemistry | 2011

von Cheong, S. | Dolzhenko, A. | Paoletta, S. | +8

63

Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists

enthalten in: Bioorganic & medicinal chemistry letters | 2011

von Cheong, S. | Federico, S. | Venkatesan, G. | +5

64

Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists

enthalten in: Bioorganic & medicinal chemistry letters | 2011

von Cheong, S. | Federico, S. | Venkatesan, G. | +5

65

Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility

enthalten in: Journal of medicinal chemistry | 2011

von Federico, S. | Paoletta, S. | Cheong, S. | +9

66

Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A2A Adenosine Receptor Antagonists with Improved Water Solubility

enthalten in: Journal of medicinal chemistry | 2011

von Federico, S. | Paoletta, S. | Cheong, S. | +9

67

Pyrazolo derivatives as potent adenosine receptor antagonists : an overview on the structure-activity relationships

enthalten in: International journal of medicinal chemistry | 2011

von Cheong, S. | Venkatesan, G. | Paira, P. | +5

68

The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists : new insights into structure-affinity relationship and receptor-antagonist recognition

enthalten in: Journal of medicinal chemistry | 2010

von Cheong, S. | Dolzhenko, A. | Kachler, S. | +8

69

The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3 Adenosine Receptors Antagonists: New Insights into Structure−Affinity Relationship and Receptor−Antagonist Recognition

enthalten in: Journal of medicinal chemistry | 2010

von Cheong, S. | Dolzhenko, A. | Kachler, S. | +8

70

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists : A preliminary inspection of ligand-receptor recognition process

enthalten in: Bioorganic & medicinal chemistry | 2010

von Pastorin, G. | Federico, S. | Paoletta, S. | +8