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journalStr:"Journal of medicinal chemistry"
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PubPharm (70)
1
Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target
enthalten in:
Journal of medicinal chemistry
| 2024
von
Wazir, S.
|
Parviainen, T.
|
Pfannenstiel, J.
| +9
UpdateOf: bioRxiv. 2023 Dec 27;:. - PMID 38234730
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2
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease
enthalten in:
Journal of medicinal chemistry
| 2024
von
Alugubelli, Y.
|
Xiao, J.
|
Khatua, K.
| +12
UpdateOf: bioRxiv. 2023 Sep 29;:. - PMID 37808777
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3
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic
enthalten in:
Journal of medicinal chemistry
| 2024
von
Shurtleff, V.
|
Layton, M.
|
Parish, C.
| +45
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4
Antiviral Protein-Protein Interaction Inhibitors
enthalten in:
Journal of medicinal chemistry
| 2024
von
Marković, V.
|
Szczepańska, A.
|
Berlicki, .
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5
Discovery of a Macrocyclic Influenza Cap-Dependent Endonuclease Inhibitor
enthalten in:
Journal of medicinal chemistry
| 2024
von
Feng, J.
|
Guo, F.
|
Li, P.
| +10
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6
Discovery of CMX990 : A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead
enthalten in:
Journal of medicinal chemistry
| 2024
von
Dayan Elshan, N.
|
Wolff, K.
|
Riva, L.
| +28
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7
Halogenated Rocaglate Derivatives : Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses
enthalten in:
Journal of medicinal chemistry
| 2024
von
Victoria, C.
|
Schulz, G.
|
Klöhn, M.
| +9
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8
Protective Efficacy of Novel Engineered Human ACE2-Fc Fusion Protein Against Pan-SARS-CoV-2 Infection In Vitro and in Vivo
enthalten in:
Journal of medicinal chemistry
| 2023
von
Yu, B.
|
Drelich, A.
|
Hsu, J.
| +9
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9
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability
enthalten in:
Journal of medicinal chemistry
| 2023
von
Gao, S.
|
Song, L.
|
Sylvester, K.
| +12
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10
Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys
enthalten in:
Journal of medicinal chemistry
| 2023
von
Mackman, R.
|
Kalla, R.
|
Babusis, D.
| +31
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Zeitschrift: Journal of medicinal chemistry
Medienart
70
Aufsätze
66
E-Artikel
66
E-Ressourcen
4
Gedruckte Aufsätze
Zeitschriftentitel
Journal of medicinal chemistry
Thema
70
Antiviral Agents
68
Journal Article
45
Research Support, Non-U.S. Gov't
26
Coronavirus 3C Proteases
26
EC 3.4.22.28
25
EC 3.4.22.-
24
Protease Inhibitors
22
Research Support, N.I.H., Extramural
15
3C-like proteinase, SARS-CoV-2
13
Review
12
Cysteine Endopeptidases
9
Cysteine Proteinase Inhibitors
7
Research Support, U.S. Gov't, Non-P.H.S.
6
Viral Nonstructural Proteins
5
EC 3.4.-
5
EC 3.4.22.2
5
Peptides
5
Spike Glycoprotein, Coronavirus
5
spike protein, SARS-CoV-2
4
Cysteine
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Erscheinungszeitraum
62
2020-
3
2010-2019
5
2000-2009
Erscheinungsjahr(e)
Von:
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Sprache
70
Englisch
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