Thema
Rucaparib
13
Journal Article
9
Pharmacokinetics
9
rucaparib
8
8237F3U7EH
7
Indoles
7
PARP inhibitor
6
Poly(ADP-ribose) Polymerase Inhibitors
6
Antineoplastic Agents
5
Safety
5
Hepatic impairment
4
Human ADME study
4
Mass balance
4
Metabolite identification
4
Poly(ADP-ribose) polymerase inhibitor
4
Poly(ADP-ribose) polymerase inhibitors
4
Population pharmacokinetics
4
Research Support, Non-U.S. Gov't
4
Solid tumors
4
Clinical Trial, Phase I
3
BCRP
2
EC 1.14.14.1
2
EC 3.4.21.-
2
EC 3.4.21.59
2
MATE)
2
OAT
2
OCT)
2
Serine Endopeptidases
2
Tryptases
2
drug-drug interactions
2
efflux transporters (P-gp
2
uptake transporters (OATP
2
49DFR088MY
1
9035-51-2
1
ABCB1 protein, human
1
ATP Binding Cassette Transporter, Subfamily B
1
ATP Binding Cassette Transporter, Subfamily G, Member 2
1
BRCA1 Protein
1
BRCA1 protein, human
1
Carbon Radioisotopes
1
Cytochrome P-450 CYP1A2
1
Cytochrome P-450 CYP3A
1
Cytochrome P-450 Enzyme System
1
EC 2.4.2.30
1
EC 3.4.21.9
1
Efficacy
1
Enteropeptidase
1
Enzyme Inhibitors
1
Exposure
1
Membrane Transport Proteins
1
mehr ...