Associated Risk Factors and Pathogen Burden among ICU Patients in a Tertiary Care Hospital in Hail Saudi Arabia with Particular Reference to β-Lactamases Profile

A 1-year prospective study was carried out on patients in the ICU unit at a tertiary care hospital, Hail, Kingdom of Saudi Arabia. A total of 163 bacterial isolates were obtained from different clinical specimens with a high proportion of bacteria found associated with ventilator-associated pneumoniae (70, 43%), followed by catheter-associated urinary tract infection (39, 24%), central line-associated bloodstream infection (25, 15%), and surgical site infection (14, 8.6%). Klebsiella pneumoniae was the most common isolate (39, 24%), followed by Acinetobacter baumannii (35, 21.47%), Pseudomonas aeruginosa (25, 15%), and Proteus spp (23, 14%). Among the highly prevalent bacterial isolates, extended-spectrum beta-lactamase was predominant (42, 42.4%). Proper use of antibiotics, continuous monitoring of drug sensitivity patterns, and taking all precautionary measures to prevent beta-lactamases-producing organisms in the clinical settings are crucial and significant factors to fend off life-threatening infections and for a better outcome..

Medienart:

Preprint

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Preprints.org - (2022) vom: 02. Aug. Zur Gesamtaufnahme - year:2022

Sprache:

Englisch

Beteiligte Personen:

Mohd, Saleem [VerfasserIn]
Syed Khaja, Azharuddin Sajid [VerfasserIn]
Hossain, Ashfaque [VerfasserIn]
Alenazi, Fahaad [VerfasserIn]
Said, Kamaleldin B [VerfasserIn]
Moursi, Soha Abdallah [VerfasserIn]
Almalaq, Homoud Abdulmohsin [VerfasserIn]
Mohamed, Hamza [VerfasserIn]
Rakha, Ehab [VerfasserIn]
Salem Alharbi, Mohammed [VerfasserIn]
Usman, Kauser [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

500
Life Sciences

doi:

10.20944/preprints202207.0459.v1

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

preprintsorg036769681