Intraductal papillary neoplasm of the bile duct with infiltrative small cell neuroendocrine carcinoma: A case report
Abstract Introduction: We present the case of an intraductal papillary neoplasm of the bile duct (IPNB) accompanying a small cell neuroendocrine carcinoma. Patient concerns: A 73-year-old male Chinese patient presented with jaundice of unknown origin. A contrast-enhanced computed tomography scan revealed that the wall of the lower common bile duct was thickened and nodular, causing a narrowing in the lumen and upper common bile duct enlargement above the narrow segment. Diagnosis and interventions: The initial diagnosis based on clinical manifestations was IPNB and pancreatoduodenectomy was performed. Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia, indicating IPNB. Immunohistochemistry was positive for neuroendocrine markers indicative of infiltration and small cell neuroendocrine cancer. Outcomes: The patient died on postoperative day 138. Conclusion: This is the first reported case of its kind, as none has been reported in any published literature so far..
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Preprint| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
ResearchSquare.com - (2021) vom: 19. Okt. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhao, Baoyi [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| doi: |
10.21203/rs.3.rs-338309/v1 |
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XRA034179224 |
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| 245 | 1 | 0 | |a Intraductal papillary neoplasm of the bile duct with infiltrative small cell neuroendocrine carcinoma: A case report |
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| 520 | |a Abstract Introduction: We present the case of an intraductal papillary neoplasm of the bile duct (IPNB) accompanying a small cell neuroendocrine carcinoma. Patient concerns: A 73-year-old male Chinese patient presented with jaundice of unknown origin. A contrast-enhanced computed tomography scan revealed that the wall of the lower common bile duct was thickened and nodular, causing a narrowing in the lumen and upper common bile duct enlargement above the narrow segment. Diagnosis and interventions: The initial diagnosis based on clinical manifestations was IPNB and pancreatoduodenectomy was performed. Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia, indicating IPNB. Immunohistochemistry was positive for neuroendocrine markers indicative of infiltration and small cell neuroendocrine cancer. Outcomes: The patient died on postoperative day 138. Conclusion: This is the first reported case of its kind, as none has been reported in any published literature so far. | ||
| 700 | 1 | |a Lin, Hua-jun |e verfasserin |4 aut | |
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