Outcome of ECMO and CRRT, experience of Hospital University MED VI, Oujda, Morocco.
Abstract Background: Although acute kidney injury (AKI) is a frequent complication in patients receiving extracorporeal membrane oxygenation (ECMO), and the CRRT impact is widely studied. The incidence of simultaneous use of ECMO and CRRT remain unclear. Objective: We conducted this retrospective study to define the incidence of concomitant CRRT with ECMO therapy and to determine the overall impact of this strategy on patient outcomes such as mortality and renal recovery. Methods: We retrospectively analyzed data of patients of all ages, genders and ethnicities, admitted in the intensive care unit of Mohammed VI University Hospital, Oujda, Morocco, on a cumulative period of 2 years (January 2019 – December 2020). Were enrolled in the study patients who benefited from ECMO, and presented an acute kidney injury afterwards, using ‘Microsoft Excel’ as a software to utilize the information collected from the computerized patient database. 30 patients were included in the final study. Results: 30 patients with ECMO were enrolled. The mean age was 59.8 ± 12.7 years, with a male predominance (sex ratio (M/F) of 3.28). Over one third of the patients had comorbidities, Diabetes mellitus was the most common (30%), followed by hypertension (17%). 83.3% of our patients benefitted from a veno-venous type of ECMO; and ARDS was the most frequent cause for using ECMO comparing to cardiac failure (90% vs 16.6%). 63.3% of our ECMO-using patients developed an AKI, with a mean creatinine peak of 28.74mg/L. 36.6% of our ECMO-using patients required the use of a continuous renal replacement therapy (CRRT). Unfortunately, all our ECMO-using patients complicated with AKI died, with a mortality rate of 100%. Conclusion: Among patients receiving ECMO, the incidence rates of AKI and severe AKI requiring CRRT are high, regardless of their prior medical conditions and the technique used to connect ECMO and CRRT..
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Preprint| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
ResearchSquare.com - (2021) vom: 05. Nov. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
oujidi, younes [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| doi: |
10.21203/rs.3.rs-948539/v1 |
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XRA033478465 |
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| 520 | |a Abstract Background: Although acute kidney injury (AKI) is a frequent complication in patients receiving extracorporeal membrane oxygenation (ECMO), and the CRRT impact is widely studied. The incidence of simultaneous use of ECMO and CRRT remain unclear. Objective: We conducted this retrospective study to define the incidence of concomitant CRRT with ECMO therapy and to determine the overall impact of this strategy on patient outcomes such as mortality and renal recovery. Methods: We retrospectively analyzed data of patients of all ages, genders and ethnicities, admitted in the intensive care unit of Mohammed VI University Hospital, Oujda, Morocco, on a cumulative period of 2 years (January 2019 – December 2020). Were enrolled in the study patients who benefited from ECMO, and presented an acute kidney injury afterwards, using ‘Microsoft Excel’ as a software to utilize the information collected from the computerized patient database. 30 patients were included in the final study. Results: 30 patients with ECMO were enrolled. The mean age was 59.8 ± 12.7 years, with a male predominance (sex ratio (M/F) of 3.28). Over one third of the patients had comorbidities, Diabetes mellitus was the most common (30%), followed by hypertension (17%). 83.3% of our patients benefitted from a veno-venous type of ECMO; and ARDS was the most frequent cause for using ECMO comparing to cardiac failure (90% vs 16.6%). 63.3% of our ECMO-using patients developed an AKI, with a mean creatinine peak of 28.74mg/L. 36.6% of our ECMO-using patients required the use of a continuous renal replacement therapy (CRRT). Unfortunately, all our ECMO-using patients complicated with AKI died, with a mortality rate of 100%. Conclusion: Among patients receiving ECMO, the incidence rates of AKI and severe AKI requiring CRRT are high, regardless of their prior medical conditions and the technique used to connect ECMO and CRRT. | ||
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