Traveling waves link human visual and frontal cortex during working memory-guided behavior
Summary Working Memory (WM) enables flexible behavior by forming a temporal bridge between recent sensory events and possible actions. Through re-analysis of published human EEG studies, we show that successful WM-guided behaviors are accompanied by bidirectional cortical traveling waves linking sensory areas implicated in WM storage with frontal areas implicated in response selection and production. We identified a feedforward (occipital-to-frontal) theta wave that emerged shortly after a response probe and whose latency predicted intra- and inter-individual differences in response initiation, and a feedback (frontal-to-occipital) beta wave that emerged after response termination. Importantly, both waveforms were only observed during an overt motor response: when participants could select task-relevant WM content and prepare but not yet execute a task-appropriate action, neither waveform was observed. Our observations suggest that cortical traveling waves play an important role in the generation and execution of WM-guided behaviors..
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Preprint| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
bioRxiv.org - (2024) vom: 16. Apr. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Luo, Canhuang [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| doi: |
10.1101/2024.03.12.584543 |
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| PPN (Katalog-ID): |
XBI042900522 |
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| 520 | |a Summary Working Memory (WM) enables flexible behavior by forming a temporal bridge between recent sensory events and possible actions. Through re-analysis of published human EEG studies, we show that successful WM-guided behaviors are accompanied by bidirectional cortical traveling waves linking sensory areas implicated in WM storage with frontal areas implicated in response selection and production. We identified a feedforward (occipital-to-frontal) theta wave that emerged shortly after a response probe and whose latency predicted intra- and inter-individual differences in response initiation, and a feedback (frontal-to-occipital) beta wave that emerged after response termination. Importantly, both waveforms were only observed during an overt motor response: when participants could select task-relevant WM content and prepare but not yet execute a task-appropriate action, neither waveform was observed. Our observations suggest that cortical traveling waves play an important role in the generation and execution of WM-guided behaviors. | ||
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