The real-world evidence to the effects of primary psychological healthcare system in diluting risks of suicide ideation in underrepresented children/adolescents: an observational, multi-center, population-based, and longitudinal study
Background Establishing primary psychological healthcare system to prevent suicide was eagerly advocated. However, it remains unclear whether such policy-driven and low-cost healthcare systems could be practical, especially with equal benefits for underrepresented children/adolescents. We aimed to examine the real-world practical effects of primary psychological healthcare system in preventing suicide ideation among children/adolescents, particularly underprivileged ones. Method and Findings The study employed an observational, multi-center, population-based and longitudinal design. 19,140 children/adolescents sampled from lower- and middle-income areas of western China (Nanchong) with 1-year followed-ups were included, of which majority to underrepresented underprivileged ones. The primary outcome was the incidence for reporting severe suicide ideation after practicing primary psychological healthcare system at 0.5-year and 1-year follow-ups, as contrasts to baseline. Subgroup analysis was conducted to examine the equal benefits of system for underrepresented children/adolescents. After instigating such system, the risks of reporting suicide ideation for included children/adolescents were found significantly lower compared with the control group at 0.5-year (adjust odds ratios [aOR] 0.28, 95%CI 0.23-0.33; p<0.001) and 1-year follow-ups (aOR 0.28, 95%CI 0.23-0.33; p<0.001). The effects were also observed among underrepresented children/adolescents including “left-behind” children/adolescents, “single-parent” children/adolescents and children/adolescents in especially difficult circumstance (CEDC, all pcorrected < 0.001). The effects in CEDC and “left-behind” children/adolescents were found non-inferior to typical developing cohort (all pcorrected < 0.01). Conclusions Primary psychological healthcare system was practically effective in reducing risks of suicide ideation in children/adolescents in 1-year, at least, but not yet with fully equal benefits for all the underprivileged ones..
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Preprint| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
bioRxiv.org - (2024) vom: 27. Feb. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Wei [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
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| doi: |
10.1101/2024.02.25.24303358 |
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| funding: |
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| PPN (Katalog-ID): |
XBI042650321 |
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| 035 | |a (biorXiv)10.1101/2024.02.25.24303358 | ||
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| 041 | |a eng | ||
| 100 | 1 | |a Li, Wei |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a The real-world evidence to the effects of primary psychological healthcare system in diluting risks of suicide ideation in underrepresented children/adolescents: an observational, multi-center, population-based, and longitudinal study |
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| 520 | |a Background Establishing primary psychological healthcare system to prevent suicide was eagerly advocated. However, it remains unclear whether such policy-driven and low-cost healthcare systems could be practical, especially with equal benefits for underrepresented children/adolescents. We aimed to examine the real-world practical effects of primary psychological healthcare system in preventing suicide ideation among children/adolescents, particularly underprivileged ones. Method and Findings The study employed an observational, multi-center, population-based and longitudinal design. 19,140 children/adolescents sampled from lower- and middle-income areas of western China (Nanchong) with 1-year followed-ups were included, of which majority to underrepresented underprivileged ones. The primary outcome was the incidence for reporting severe suicide ideation after practicing primary psychological healthcare system at 0.5-year and 1-year follow-ups, as contrasts to baseline. Subgroup analysis was conducted to examine the equal benefits of system for underrepresented children/adolescents. After instigating such system, the risks of reporting suicide ideation for included children/adolescents were found significantly lower compared with the control group at 0.5-year (adjust odds ratios [aOR] 0.28, 95%CI 0.23-0.33; p<0.001) and 1-year follow-ups (aOR 0.28, 95%CI 0.23-0.33; p<0.001). The effects were also observed among underrepresented children/adolescents including “left-behind” children/adolescents, “single-parent” children/adolescents and children/adolescents in especially difficult circumstance (CEDC, all pcorrected < 0.001). The effects in CEDC and “left-behind” children/adolescents were found non-inferior to typical developing cohort (all pcorrected < 0.01). Conclusions Primary psychological healthcare system was practically effective in reducing risks of suicide ideation in children/adolescents in 1-year, at least, but not yet with fully equal benefits for all the underprivileged ones. | ||
| 650 | 4 | |a Biology |7 (dpeaa)DE-84 | |
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| 700 | 1 | |a Liu, Xuerong |4 aut | |
| 700 | 1 | |a Zhang, Qianyu |0 (orcid)0009-0006-7606-2218 |4 aut | |
| 700 | 1 | |a Tian, Xiaobing |0 (orcid)0000-0003-2695-0904 |4 aut | |
| 700 | 1 | |a Ren, Jidong |4 aut | |
| 700 | 1 | |a Han, Xiaodi |4 aut | |
| 700 | 1 | |a Shen, Chang |4 aut | |
| 700 | 1 | |a Li, Yanyan |0 (orcid)0000-0001-8834-0103 |4 aut | |
| 700 | 1 | |a Chen, Ji |4 aut | |
| 700 | 1 | |a Xia, Lei |4 aut | |
| 700 | 1 | |a Zhang, Jingxuan |4 aut | |
| 700 | 1 | |a Wu, Yi |4 aut | |
| 700 | 1 | |a Gong, Jie |4 aut | |
| 700 | 1 | |a Lan, Hai |4 aut | |
| 700 | 1 | |a Wu, Yan |4 aut | |
| 700 | 1 | |a Feng, Zhengzhi |4 aut | |
| 700 | 1 | |a Chen, Zhiyi |0 (orcid)0000-0003-1744-4647 |4 aut | |
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