Prenatal cannabis exposure is associated with localized brain differences that partially mediate associations with increased adolescent psychopathology

Abstract Prenatal cannabis exposure (PCE) is associated with mental health problems, but the neurobiological mechanisms remain unknown. We find that PCE is associated with localized differences across neuroimaging metrics that longitudinally mediate associations with mental health in adolescence (n=9,322-10,186). Differences in brain development may contribute to PCE-related variability in adolescent mental health..

Medienart:

Preprint

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

bioRxiv.org - (2023) vom: 19. Okt. Zur Gesamtaufnahme - year:2023

Sprache:

Englisch

Beteiligte Personen:

Baranger, David AA [VerfasserIn]
Miller, Alex P [VerfasserIn]
Gorelik, Aaron J [VerfasserIn]
Paul, Sarah E [VerfasserIn]
Hatoum, Alexander S [VerfasserIn]
Johnson, Emma C [VerfasserIn]
Colbert, Sarah MC [VerfasserIn]
Smyser, Christopher D [VerfasserIn]
Rogers, Cynthia E [VerfasserIn]
Bijsterbosch, Janine D [VerfasserIn]
Agrawal, Arpana [VerfasserIn]
Bogdan, Ryan [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

570
Biology

doi:

10.1101/2023.09.19.23295792

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

XBI040915689