Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes
Abstract Using the children’s toy, Shrinky-Dink ©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 0.1 fg mL−1 of the S1 subunit of the spike protein..
| Medienart: |
|
|---|
Preprint| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
bioRxiv.org - (2020) vom: 20. Nov. Zur Gesamtaufnahme - year:2020 |
|---|
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zakashansky, Julia A. [VerfasserIn] |
|---|
| Links: |
Volltext [kostenfrei] |
|---|
| doi: |
10.1101/2020.11.14.20231811 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
XBI019361335 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | XBI019361335 | ||
| 003 | DE-627 | ||
| 005 | 20230429082519.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201118s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1101/2020.11.14.20231811 |2 doi | |
| 035 | |a (DE-627)XBI019361335 | ||
| 035 | |a (DE-599)biorXiv10.1101/2020.11.14.20231811 | ||
| 035 | |a (biorXiv)10.1101/2020.11.14.20231811 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 570 |q DE-84 | |
| 100 | 1 | |a Zakashansky, Julia A. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Abstract Using the children’s toy, Shrinky-Dink ©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 0.1 fg mL−1 of the S1 subunit of the spike protein. | ||
| 700 | 1 | |a Imamura, Amanda H. |e verfasserin |4 aut | |
| 700 | 1 | |a Salgado, Darwin F. |e verfasserin |4 aut | |
| 700 | 1 | |a Romero Mercieca, Heather C. |e verfasserin |4 aut | |
| 700 | 1 | |a Aguas, Raphael F.L. |e verfasserin |4 aut | |
| 700 | 1 | |a Lao, Angelou M. |e verfasserin |4 aut | |
| 700 | 1 | |a Pariser, Joseph |e verfasserin |4 aut | |
| 700 | 1 | |a Arroyo-Currás, Netzahualcóyotl |e verfasserin |4 aut | |
| 700 | 1 | |a Khine, Michelle |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t bioRxiv.org |g (2020) vom: 20. Nov. |
| 773 | 1 | 8 | |g year:2020 |g day:20 |g month:11 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1101/2020.11.14.20231811 |z kostenfrei |3 Volltext |
| 912 | |a GBV_XBI | ||
| 912 | |a SSG-OLC-PHA | ||
| 951 | |a AR | ||
| 952 | |j 2020 |b 20 |c 11 | ||
| 953 | |2 045F |a 570 | ||