Dynamical SPQEIR model assesses the effectiveness of non-pharmaceutical interventions against COVID-19 epidemic outbreaks
Abstract Against the current COVID-19 pandemic, governments worldwide have devised a variety of non-pharmaceutical interventions to suppress it, but the efficacy of distinct measures is not yet well quantified. In this paper, we propose a novel tool to achieve this quantification. In fact, this paper develops a new extended epidemic SEIR model, informed by a socio-political classification of different interventions, to assess the value of several suppression approaches. First, we inquire the conceptual effect of suppression parameters on the infection curve. Then, we illustrate the potential of our model on data from a number of countries, to perform cross-country comparisons. This gives information on the best synergies of interventions to control epidemic outbreaks while minimising impact on socio-economic needs. For instance, our results suggest that, while rapid and strong lock-down is an effective pandemic suppression measure, a combination of social distancing and contact tracing can achieve similar suppression synergistically. This quantitative understanding will support the establishment of mid- and long-term interventions, to prepare containment strategies against further outbreaks. This paper also provides an online tool that allows researchers and decision makers to interactively simulate diverse scenarios with our model..
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Preprint| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
bioRxiv.org - (2024) vom: 23. Apr. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
Proverbio, Daniele [VerfasserIn] |
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| doi: |
10.1101/2020.04.22.20075804 |
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| PPN (Katalog-ID): |
XBI017747988 |
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| 520 | |a Abstract Against the current COVID-19 pandemic, governments worldwide have devised a variety of non-pharmaceutical interventions to suppress it, but the efficacy of distinct measures is not yet well quantified. In this paper, we propose a novel tool to achieve this quantification. In fact, this paper develops a new extended epidemic SEIR model, informed by a socio-political classification of different interventions, to assess the value of several suppression approaches. First, we inquire the conceptual effect of suppression parameters on the infection curve. Then, we illustrate the potential of our model on data from a number of countries, to perform cross-country comparisons. This gives information on the best synergies of interventions to control epidemic outbreaks while minimising impact on socio-economic needs. For instance, our results suggest that, while rapid and strong lock-down is an effective pandemic suppression measure, a combination of social distancing and contact tracing can achieve similar suppression synergistically. This quantitative understanding will support the establishment of mid- and long-term interventions, to prepare containment strategies against further outbreaks. This paper also provides an online tool that allows researchers and decision makers to interactively simulate diverse scenarios with our model. | ||
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| 700 | 1 | |a Kemp, Françoise |e verfasserin |0 (orcid)0000-0001-5845-293X |4 aut | |
| 700 | 1 | |a Magni, Stefano |e verfasserin |0 (orcid)0000-0001-8649-3616 |4 aut | |
| 700 | 1 | |a Husch, Andreas |e verfasserin |0 (orcid)0000-0001-9404-5127 |4 aut | |
| 700 | 1 | |a Aalto, Atte |e verfasserin |0 (orcid)0000-0002-6876-474X |4 aut | |
| 700 | 1 | |a Mombaerts, Laurent |e verfasserin |0 (orcid)0000-0002-8653-7348 |4 aut | |
| 700 | 1 | |a Skupin, Alexander |e verfasserin |0 (orcid)0000-0002-8955-8304 |4 aut | |
| 700 | 1 | |a Gonçalves, Jorge |e verfasserin |0 (orcid)0000-0002-5228-6165 |4 aut | |
| 700 | 1 | |a Ameijeiras-Alonso, Jose |e verfasserin |0 (orcid)0000-0002-4122-6992 |4 aut | |
| 700 | 1 | |a Ley, Christophe |e verfasserin |0 (orcid)0000-0002-2290-8437 |4 aut | |
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