Pulvinar neuromodulation for seizure monitoring and network modulation in temporal plus epilepsy
ABSTRACT Deep brain stimulation (DBS) is a promising treatment for drug‐refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15–17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real‐time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Annals of Clinical and Translational Neurology - 10(2023), 7, Seite 1254-1259 |
| Beteiligte Personen: |
Vakilna, Yash Shashank [VerfasserIn] |
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| Anmerkungen: |
© 2023 American Neurological Association |
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| Umfang: |
1259 |
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| doi: |
10.1002/acn3.51815 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
WLY014763850 |
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| 520 | |a ABSTRACT Deep brain stimulation (DBS) is a promising treatment for drug‐refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15–17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real‐time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection. | ||
| 700 | 1 | |a Chaitanya, Ganne |4 aut | |
| 700 | 1 | |a Hafeez, Muhammad Ubaid |4 aut | |
| 700 | 1 | |a Ilyas, Adeel |4 aut | |
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| 700 | 1 | |a Tandon, Nitin |4 aut | |
| 700 | 1 | |a Pati, Sandipan |4 aut | |
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