Long‐Term COVID‐19 Smell and Taste Disorders Differ Significantly from Other Post‐Infectious Cases
Introduction COVID‐19 is causing a wide range of clinical manifestations. Severe complications and long‐lasting sequelae have been identified. Thus, olfactory disorders are reported in up to 86% of cases in mild and moderate COVID‐19 infections. We present the first study comparing simple and complex post‐COVID‐19 cases with matched non‐COVID‐19 post‐infectious smell and taste disorders. Methods A total of 328 patients were recruited from the University Clinic for Flavour, Balance and Sleep, Ear‐nose‐throat Department, Goedstrup Hospital, Denmark. A non‐COVID ‐19 post‐infectious population of 148 individuals was identified from the Redcap database, and was matched by duration of smell and taste disorders. Post‐COVID‐19 patients were divided into 99 patients with simple smell and taste disorders (only suffering from smell and taste disorders after COVID‐19); and (81 patients with complex smell and taste disorder plus several other post‐COVID‐19 complaints). Besides patient‐reported outcome measures (PROM) questionnaires and quality of life score (QoL), ear‐nose‐throat examination, Mini‐Mental State Examination (MMSE), orthonasal smell test (Sniffing's sticks), retronasal quick test, and taste screening were performed. Results Cases with post‐COVID‐19‐related smell and taste disorders deviated from non‐COVID‐19 post‐infectious cases; the patients were younger, had a lower occurrence of anosmia/ageusia, and had higher overall smell test scores. In contrast, patients with post‐COVID‐19‐related smell and taste disorders more frequently complained of distorted senses. Parosmia and phantosmia were more prevalent among patients with simple post‐COVID‐19 complaints than among complex cases and their QoL were more negatively affected. Conclusion Smell and taste function differ significantly between post‐COVID‐19 and other non‐COVID‐19 post‐viral cases. Level of Evidence3 Laryngoscope, 133:169–174, 2023.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:133 |
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| Enthalten in: |
The Laryngoscope - 133(2023), 1, Seite 169-174 |
| Beteiligte Personen: |
Stankevice, Dovile [VerfasserIn] |
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| BKL: |
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| Anmerkungen: |
© 2023 The American Laryngological, Rhinological and Otological Society, Inc. |
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| Umfang: |
6 |
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| doi: |
10.1002/lary.30453 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Introduction COVID‐19 is causing a wide range of clinical manifestations. Severe complications and long‐lasting sequelae have been identified. Thus, olfactory disorders are reported in up to 86% of cases in mild and moderate COVID‐19 infections. We present the first study comparing simple and complex post‐COVID‐19 cases with matched non‐COVID‐19 post‐infectious smell and taste disorders. Methods A total of 328 patients were recruited from the University Clinic for Flavour, Balance and Sleep, Ear‐nose‐throat Department, Goedstrup Hospital, Denmark. A non‐COVID ‐19 post‐infectious population of 148 individuals was identified from the Redcap database, and was matched by duration of smell and taste disorders. Post‐COVID‐19 patients were divided into 99 patients with simple smell and taste disorders (only suffering from smell and taste disorders after COVID‐19); and (81 patients with complex smell and taste disorder plus several other post‐COVID‐19 complaints). Besides patient‐reported outcome measures (PROM) questionnaires and quality of life score (QoL), ear‐nose‐throat examination, Mini‐Mental State Examination (MMSE), orthonasal smell test (Sniffing's sticks), retronasal quick test, and taste screening were performed. Results Cases with post‐COVID‐19‐related smell and taste disorders deviated from non‐COVID‐19 post‐infectious cases; the patients were younger, had a lower occurrence of anosmia/ageusia, and had higher overall smell test scores. In contrast, patients with post‐COVID‐19‐related smell and taste disorders more frequently complained of distorted senses. Parosmia and phantosmia were more prevalent among patients with simple post‐COVID‐19 complaints than among complex cases and their QoL were more negatively affected. Conclusion Smell and taste function differ significantly between post‐COVID‐19 and other non‐COVID‐19 post‐viral cases. Level of Evidence3 Laryngoscope, 133:169–174, 2023 | ||
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